摘要
目的:了解输血传播病毒(TTV)在各型肝炎患者中的感染情况。方法:采用套式PCR方法,对218 例不同型别的肝炎病人血清进行TTV-DNA检测。结果:218 例不同肝炎病人中共检出72 例TTV-DNA阳性血清,总检出率为33.0%,不同民族、性别间TTV-DNA 阳性率差异无统计学意义(P>0.05)。其中排除非甲非戊型肝炎单纯转氨酶增高病人中TTV-DNA阳性率为53.9%,而在明确诊断为甲型、乙型、丙型肝炎病人中TTV-DNA阳性率为26.5%,两组相比差异有统计学意义(χ2=13.38,P<0.05)。结论:各型肝炎患者中存在TTV感染,非甲非戊型肝炎单纯转氨酶增高病人中TTV感染率明显高于明确病原肝炎病人。TTV感染与肝炎有关,可能是原因不明肝炎的病因之一。
Objective: To study the prevalence of transfusion transmitted virus (TTV) in hepatitis patients. Methods:Sera from hepatitis patients were tested by nested polymerase chain reaction (nPCR) assay for the presence of TTV DNA. Results:The total detection rate of TTV DNA in those 218 objects was 33.0%. The TTV positive rate was 53.9% in non A E hepatitis, but 26.5 % in hepatitis patients whose diagnosis were clear. There was no relationship between TTV infection with nationalities、sex of hepatitis patients. Conclusion: TTV infection may be one of the cause of non A E hepatitis.
出处
《新疆医科大学学报》
CAS
2005年第2期118-119,共2页
Journal of Xinjiang Medical University
关键词
输血传播病毒
肝炎
聚合酶链式反应
transfusion transmitted virus (TTV)
hepatitis
polymerase chain reaction (PCR)
