摘要
本文报告了１８例中线非何杰金氏恶性淋巴瘤电镜研究结果，其中Ｔ细胞型１６例，Ｂ细胞型２例。１８例中多形细胞型１４例，透明细胞型、小淋巴细胞型、无裂细胞型及裂细胞型各１例。多形细胞型中的大、中型瘤细胞中有较丰富、畸形的内质网，线粒体扩张，嵴减少或消失而表现出异形性；大型瘤细胞的核大，常染色质丰富和易见的核仁均说明其蛋白质合成机能旺盛，瘤细胞增生活跃。瘤组织中大、中型细胞越多，其恶性度越高。透明细胞型以大、中型细胞为主，显示出其高度恶性。无裂细胞型以不规则细胞突起文错存在而表现为瘤细胞成团存在，形成滤泡样结构，限制其瘤细胞的浸润、迁移，其恶性度较弥漫性增生者为低。相反后者则易于扩散、浸润，预后差。
Eighteen cases of midline Non- Hodgkin's malignant lymphomas were studied using electron
mi- croscopy. The results indicated that 1 6 cases,of midline Non- Hodgkin's malignant ly
mphomas were Tcell lymphomas and the other 2 cases were Bcell lymphomas.According to
project of clinical classifi-eation about Non- Hodgkin's lymphoma,14 cases were pleomorphism
type;the other 4 cases were hyalocyte((clear cell)small lymphocyte schistocyte and
un-schistocyte type。There were deforma-tional and richer endoplasmic reticulum(ER)in large
and medium cells of the pleomorphism and its mitochon drion expended and mitochondrial
crista reduced or disappeared.The exu berant protein oflarge cell was to be compound in which
showin8 (appearing)larger nudeus,clearner nucleolus andricher autosome。The more there
were large and medium cells in tumour tissue,the more malig nanttumour was.The large and
medium cells were main cell of hga locyte type existing a ball un-schisto-cyte had unregular
cell process,and formed follicle structure. The structure would control diffusion oftumour cells
on the contrary,non-follicular type is more malignant than follicular type at spread oflymphoma.
