摘要
目的 结合WHO(2 0 0 0 )对结肠、直肠癌的诊断标准 ,对结肠、直肠内窥镜活检癌的临床病理诊断进行探讨。方法 对 12 15例结肠、直肠活检诊断癌的标本进行回顾性阅片 ,确定癌侵及黏膜下层的标准 ,并与相应的手术切除标本的病理诊断进行对照 ,进行手术前后的病理诊断分析。结果 将 12 15例活检诊断结肠、直肠癌的标本与手术切除标本对比 ,其中 1173例活检诊断结肠癌 ,其中不能肯定癌侵及黏膜下层者 74 2例 ,手术后标本均为浸润癌 ,4 2例为腺瘤癌变 ,手术后标本有 3例癌局限在黏膜内。结论 建议在结肠活检癌的病理诊断中对不能确定癌侵及黏膜下层的病例不使用黏膜内肿瘤诊断 ,因为事实上这些病例绝大多数已是浸润癌。黏膜内肿瘤诊断主要应用于腺瘤及腺瘤癌变。
Objective To study the clinical pathological diagnoses for biopsy of colorectal carcinoma based on WHO criterion(2000). Methods The pathological diagnosis of 1215 cases of colorectal cancer biopsies and corresponding surgically removed speci mens were reviewed. Results The pathological diagnosis of 1173 from 1215 cases of biopsies were colorectal carcinoma conformed to the results of the surgical specimen. That cancer invaded submucosa were not determined in 742 of 1173 cases (63.3%) by biopsies. Othe r 42 cases of adenomas with malignant transformation by biopsies were found 3 cases in which cancer confined in mucosa. Conclusion The diagnosis of “int ramucsal neoplasia' in colorectal biopsies is not applicable for tha t cas es in which that cancer invades submucosa cannot be determined, because absol ute major ity of those cases are invasive cancer in fact. Intramucosal neoplasia may be diagnosed in adenomas and adenoma-carcinoma sequence in colon biopsy.
出处
《诊断病理学杂志》
CSCD
2005年第1期8-11,i003-i004,共6页
Chinese Journal of Diagnostic Pathology
