摘要
目的 研究食管胃肠道间质瘤的临床、病理及免疫组织化学特征 ,重新认识食管间叶源性肿瘤的组成。方法 用CD117、CD34、vimentin、SMA、S 10 0蛋白 5种抗体对 4 4例食管间叶源性肿瘤进行免疫组织化学SP法染色。结果确诊食管胃肠道间质瘤 9例 ,平滑肌瘤 34例 ,神经纤维瘤 1例。结果 食管内胃肠道间质瘤少见 ,仅占同期间叶源性肿瘤的 2 0 .5 % (9 4 4 ) ,其中良性 6例 ,恶性 3例。结论 胃肠道间质瘤与其他肿瘤的鉴别诊断需要依靠免疫组织化学检测 ,CD117、CD34是诊断间质瘤的特异性抗体。
Objective To explore the histogenesis, immunohistochemical and clinicop athologic characteristics of esophageal gastrointestinal stromal tumors (GIST) . Methods 44 cases of the mesenchymal tumors in esophagus were stained b y use of a panel of antibodies such as CD117,CD34 by SP immunohistochemical me thods. There were 9 case of esophageal gastrointestinal stromal tumors, 34 cas e of leiomyomas, and 1 case of schwannoma. Results Esophage al gastrointestinal s tromal tumors were the rare mesenchymal tumors. With lig ht microscopic examination, the morphology of stromal tumors looked sometimes li k e a leiomyoma or schwannoma. Conclusion It is necessary for the differential diagnosis of esophageal GIST to use immunohistochemical makers, particulay CD117 and CD34.
出处
《诊断病理学杂志》
CSCD
2005年第1期31-33,i009,共4页
Chinese Journal of Diagnostic Pathology
