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云南16个少数民族群体的线粒体DNA多态性研究 被引量:10

Genetic Polymorphism of Mitochondrial DNA in Coding Region in 16 Ethnic Populations of Yunnan
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摘要 利用PCR RFLP法对傣族、白族、蒙古族、彝族等 1 0个少数民族的 1 6个群体共 6 5 4人进行了mtDNA编码区多态性分析 ,共检测到 1 7种单倍群 ,其中 4种为未能确认的单倍群。单倍群频率分布和主成分图共同显示 ,百越系的 3个民族共 6个群体有高频的B、F单倍群 ,聚集在图的下部 ,表现出鲜明的南方群体特征 ;蒙古族的 2个群体有高频的A、D单倍群 ,聚在图的上部 ,具有典型的北方群体特征 ;氐羌系的 5个民族共 7个群体全部或绝大多数都兼有南北方高频单倍群 ,位于图的中间 ,提示他们同时具有南北方群体的一些母系遗传特征。同一民族不同群体间的单倍群频率分布存在差异 ,但差异不很大 ,一般小于不同族源民族间的差异 。 The genetic polymorphism of mitochondrial DNA in the coding region in 16 ethnic populations of Yunnan was analyzed using PCR-RFLP in a total of 654 samples.Seventeen haplogroups were found,four of which were undefined haplogroups.Haplogroup distribution and Principal Component (PC) analysis showed that the ethnic groups descended from Bai-Yue tribe have B,F and M7 as the predominant haplogroups,which indicated their origination from southern China.Haplogroup A,D and N9 were predominant in the Mongolian ethnic group,reflecting their north-originated characteristics.The groups descended from Di-Qiang tribe shared the predominant haplogroups with both the south and north originated groups,which demonstrated that they inherit the maternal characteristics from both southern and northern populations.There is genetic difference among the populations in the same ethnic group and is usually smaller than that among the ethnic groups from different ancient tribes,but not necessarily smaller than that among the groups from the same tribe.
出处 《Acta Genetica Sinica》 SCIE CAS CSCD 北大核心 2005年第2期118-123,共6页
基金 国家自然科学基金项目 (编号 :3 0 16 0 0 3 7 3 0 2 6 90 0 1) 云南省自然科学基金项目 (编号 :2 0 0 3C0 0 0 1P)资助~~
关键词 线粒体DNA 少数民族 多态性 mitochondrial DNA ethnic population polymorphism
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  • 1姚永刚,张亚平.线粒体DNA和人类进化[J].Zoological Research,2000,21(5):392-406. 被引量:18
  • 2钱亚屏,褚嘉佑,初正韬,卫灿东,戴青,S Horai.应用线粒体DNA D-loop区遗传多样性分析云南4个少数民族的遗传关系[J].Acta Genetica Sinica,2001,28(4):291-300. 被引量:15
  • 3Anderson S,Bankier A T,Barrell B G,de Bruijn M H,Coulson A R, Drouin J, Eperon I C, Nierlich D P, Roe B A, Sanger F,Schreier P H,Smith A J,Staden R,Young I G. Sequence and organization of the human mitochondrial genome. Nature,1981,290 (5806):457~465.
  • 4Wallace D C, Brown M D, Lott M T. Mitochondrial DNA variation in human evolution and disease. Gene, 1999, 238(1):211~230.
  • 5Cann R L,Stoneking M,Wilson A C. Mitochondrial DNA and human evolution. Nature,1987,325(6099) :31~36.
  • 6Vigilant L,Stoneking M,Harpending H, Hawkes K,Wilson A C. African populations and the evolution of human mitochondrial DNA. Science,1991,253 (5027):1503~1507.
  • 7Harpending H C,Batzer M A,Gurven M,Jorde L B,Rogers A R, Sherry S T. Genetic traces of ancient demography.Proc Natl Acad Sci USA,1998,95(4):1961~1967.
  • 8Excoffier L, Schneider S. Why hunter-gatherer populations do not show signs of pleistocene demographic expansions.Proc Natl Acad Sci USA,1999,96 (19):10597~10602.
  • 9Rogers A R, Jorde L B. Genetic evidence on modern human origins. Hum Bio,1995,67 (1):1~36.
  • 10Yao Y G, Kong Q P, Bandelt H J, Kivisild T,Zhang Y P.Phylogeographic differentiation of mitochondrial DNA in Han Chinese. Am J Hum Genet,2002,70(3):635~651.

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