摘要
目的:探讨大剂量奥曲肽在肠瘘治疗中的应用价值。方法:对61例肠瘘患者进行分组,分别给予大剂量和常规剂量奥曲肽治疗,并对照观察肠瘘引流量变化、肠瘘愈合时间等临床指标。结果:大剂量奥曲肽治疗组的肠瘘引流量下降率明显高于常规治疗组和对照组(P<0.01,P<0.05);与低位肠瘘和低排量性肠瘘相比,奥曲肽治疗对于降低高位肠瘘和高排量性肠瘘的引流量更为有效(P<0.05)。结论:大剂量奥曲肽对于控制肠瘘引流量具有显著意义,可作为治疗肠瘘的有效手段。
Objective To evaluate the role of octreotide in the management of intestinal fistula. Methods Sixty one patients with intestinal fistula were divided into three groups, in which 19 patients were treated with large doses of octreotide, 22 patients were treated with normal doses of octreotide and 20 patients as control group. The change of drainage amount and the time for fistula to heal were observed. Results In the group treated with large doses of octreotide, the amount of fistula drainage was less than that in the group treated with normal dose and the control group(P< 0.01 and P< 0.05). As compared to low intestinal fistula and low output intestinal fistula, octreotide was more effective to lower the amount of drainage in high intestinal fistula and high output intestinal fistula (P< 0.05). Conclusions The treatment of large doses of octreotide is effective to control the amount of fistula drainage.
出处
《实用医学杂志》
CAS
2005年第5期521-522,共2页
The Journal of Practical Medicine
