摘要
目的分析鼻咽癌的临床特征.方法对246例鼻咽癌患者进行回顾性分析.结果 246例鼻咽癌发病年龄高峰为40～59岁,97.15%为低分化鳞癌,病变部位以鼻咽侧壁最常见.居前5位的首发症状出现率依次为:颈部肿块41.06%、鼻部症状33.74%、耳部症状15.85%、头痛6.91%、脑神经损害症状2.03%;首次就诊症状的出现率则为:颈部肿块74.39%、鼻部症状69.11%、耳部症状47.15%、头痛30.08%、脑神经损害症状27.64%.21.14%患者以单类症状就诊,脑神经损害以第Ⅴ、Ⅵ对最常见.首发症状病程均在3个月以上的占70.33%,EBV VCA-IgA、EA-IgA的阳性率分别为97.22%、73.61%.结论鼻咽癌的临床症状复杂,误诊率高,易延误诊断,出现以上症状者宜常规行鼻咽部检查和EB病毒血清学检测.
Objective To investigate the clinical presentation of patient with nasopharyngeal carcinoma (NPC).Methods The clinical data of 246 cases with NPC was analyzed retrospectively.Results The peak age stage of NPC was 40-59 years old and low differential squamous cell carcinoma was 97.15% of all cases. The tumor was usually found in the nasopharyngeal lateral wall. The primary symptoms of which patient complained firstly were represented by cervical mass in 41.06% of cases;nasal symptoms in 33.74%; otological symptoms in 15.85%; headache in 6.91%,while neurological symptoms were reported in only 2.03% of cases. On the contrary, symptoms at first diagnosis were more frequently represented by cervical mass(74.39%),nasal symptoms(69.11%), otological symptoms(47.15%), headache(30.08%) and neurological symptoms(27.64%). 21.14% of cases suffered from only one of the five symptoms. The Ⅴand Ⅵ cranial nerves were easy to be involved. The course of primary symptoms was more than three months in 70.33% of cases. The positive rate of EBV VCA-IgA and EA-IgA was 97.22%,73.61% respectively.Conclusion The clinical presentation of NPC was complex .This disease was prone to be misdiagnosed or delayed diagnosis. For a patient with any of these symptoms nasopharyngeal examination and EBV serological screening were necessary.
出处
《重庆医学》
CAS
CSCD
2005年第3期395-397,共3页
Chongqing medicine
关键词
鼻咽癌
临床表现
误诊
nasopharyngeal carcinoma
clinical presentation
misdiagnose
