摘要
新生儿缺氧缺血性脑病６２例，分２组。纳洛酮组３１例（男性２０例，女性１１例）采用常规综合治疗外加用纳洛酮０．２ｍｇ于１０％葡萄糖溶液１００ｍＬ中静脉滴注，隔１ｈ可重复，每日２－３次，共用５－７ｄ。对照组采用相同的常规综合治疗，疗程相同。结果：纳洛酮组治愈率８７％，病死率１３％，对照组依次为６８％和３２％；组间比较Ｐ＜０．０５。未发生不良反应。
Thirty-one neonates(M 20,F11)with hypoxic-ischemic encephalopathy were given naloxone 0.2 mg in 10% glucose solution 100 mL,iv every hour,twice or three times a day,for 5-7 d as a course in addition to conventional therapy.Another 31 neonates(M 21,F 10) were given routine remedies as control.Results showed that the cure rate and mortality of naloxone group were 87% and 13%;that the control group were 68% and 32%,respectively(P<0.05).No adverse reaction was observed.
出处
《新药与临床》
CSCD
北大核心
1994年第2期69-70,共2页
关键词
纳洛酮
新生儿窒息
脑缺血
naloxone
asphyxia neonatorum
cerebral ischemia
