期刊文献+

银杏叶提取物对肾急性缺血再灌注损伤家兔抗氧化能力的影响 被引量:8

Effects of extract of ginkgo biloba on oxidation and anti-oxidation in rabbits with renal ischemic reperfusion injury
下载PDF
导出
摘要 目的了解银杏叶提取物对肾急性缺血再灌注损伤家兔氧化和抗氧化能力的影响。方法将家兔随机分为4组 ,1组为假手术组、2组为缺血再灌注模型组、3组4组为银杏叶提取物治疗组 ,分别检测各组家兔血清和肾组织中超氧化物歧化酶 (saper -oxidedismutase ,SOD)活性 ,丙二醛 (malondialdihyde ,MDA)含量。结果两治疗组家兔较模型组再灌注1h、2h血清MDA含量下降 ,SOD活性升高。结论银杏叶提取物能明显提高缺血再灌注损伤家兔的抗氧化能力。 Objective To explore the effects of extract of ginkgo biloba on anti-oxidation in rabbits with renal ischemic reperfusion injury.Methods Healthy rabbits were divided into4groups ranˉdomly.GroupⅠserved as control group(false operation),groupⅡwas the model group of renal isˉcxhemic reperfusion injury groupⅢandⅣserved as the experimental groups.The amounts of SOD,MDA in the serum samples were determined respectively.Results The results showed that the amounts of MDA in the rabbits of groupⅢandⅣdecreased after reperfusion for1hour and2hours,but the amounts of SOD increased.Conclusion The results indicate that the extracts of Ginkgo Biloba can improve anti-oxidation in the rabbits with renal ischemic reperfusion injury significantly.
出处 《河北职工医学院学报》 2005年第1期4-5,共2页 Journal of Hebei Medical College for Continuing Education
  • 相关文献

参考文献4

  • 1Glaumann B,Cross CE,Paller MS,et al.Studies on the pathogenesis of the ischemic cell injury[J].Virch-ons Archiv l975,19:303.
  • 2Gelman S.The Pathophysiology of aortic ossclamping and unclamping[J].Anesthesiology,1995,82:1026.
  • 3Nicholson ML,Baker DM,Horkinson BR,et al.Ran-domized controlled trial of the effect of mannitol on renal reperfusion injury during aortic aneurysm surg-ery[J].Br J Surg,1996,83:1230.
  • 4刘福英 吕占军.实验动物学[M].北京:中国农业科技出版社,1997.87.

共引文献9

同被引文献91

引证文献8

二级引证文献53

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部