摘要
目的 探讨β2 微球蛋白(β2 MG)在病毒性脑炎发病过程中的变化。方法 采用免疫比浊分析法对 40例病毒性脑炎患儿及12名正常对照者的血清及脑脊液β2 MG水平进行检测。结果 初期各型患儿血清及 脑脊液中β2 MG即显著增高,其增高程度与病情严重程度呈正相关,恢复期血清β2 MG降至正常。结论 β2 MG参与了病毒性脑炎的发病过程,可作为判断病毒性脑炎病情及预后的一项重要指标。
Objective To evaluate the change of β 2-microglobulin(β 2-MG) level in the development of acute viral encephalitis. Methods The levels of β 2-MG in serum and cerebrospinal fluid (CSF) of 40 acute viral encephalitis children and 12 control subjects were measured by immunonephelometry. Results At initial period, the levels of β 2-MG in serum and CSF of acute viral encephalitis children were higher than that of the control group, the increasing degree was positively related to the severity of the disease. Then the level of β 2-MG in serum decreased to normal at convalescence. Conclusions β 2-MG takes part in the development of acute viral encephalitis. So it can be considered as an marker of assessment of severity and prognosis of acute viral encephalitis.
出处
《检验医学》
CAS
北大核心
2005年第2期137-139,共3页
Laboratory Medicine
关键词
Β2-微球蛋白
病毒性脑炎
脑脊液
患儿
β 2-microglobulin
Acute viral encephalitis
Cerebrospinal fluid
