摘要
目的 调查昆明成年女性髋部骨密度 (BMD)变化 ,对骨质疏松 (OP)进行筛查研究。方法 用双能X线骨吸收仪 (DEXA)测量健康女性 330名 ,左股骨颈 (Neck)、沃氏三角 (Ward s)和大转子(Troch) 3区的BMD值。结果 髋部 3区BMD峰值年龄均在 2 0～ 2 9岁 ,峰值水平Neck >Ward s >Troch ;BMD值 30岁后随年龄下降 ,绝经后 (5 0～ 5 9岁组 )失骨率显著升高 ,分别为 2 0 2 % /年 (W )、1 .32 % /年 (N)、1 0 7% /年 (T) ,70～ 79岁再次失骨加速 ,>80岁组累计失骨率 5 2 83% (W)、4 0 95 %(N)、39 97% (T)。OP筛查 :以 2 5s为标准 ,<5 0岁无OP ,之后随年龄上升 ,以Ward s三角最敏感 ;≥5 0岁患病率为 30 %～ 5 0 %。结论 30岁前达BMD峰值 ,绝经后骨丢失加快 ,存在老年第二失骨加速期 ,提示绝经和年龄先后起决定性作用 ,5 0岁后骨质疏松开始出现。筛查OP的敏感性依次为Ward s>Neck >Troch。
Objective To study the hip bone mineral density (BMD) in adult women and the prevalence rate of osteoporosis (OP) in Kunming region. Methods 330 healthy women living in Kunming, aged 20-90 years, were recruited. BMD at left femoral neck, Ward's triangle and great trochanter were measured by DEXA. Results The peak BMD appeared in 20-29 of age, the BMD at Neck>Ward's>Trock. After 30 years of age BMD declined with age, and the bone mass loss accelerated after menopausee (50-59 years of age), reaching 2.02%/year.(W), 1.32%/year(N) and 1.07%/year(T). In 70-90 age group, the bone mass loss accelerated again, and the accumulated bone mass loss reached 52.83%(W), 40.95%(N) and 39.97(T). According to the criterion of OP, there was no OP in women before 50 years of age. After 50 years of age, the prevalence rate of OP rose with age and was most sensitive in Ward's area; the average prevalence rate of OP was 30%-50%. Conclusions Peak is BMD appears in 20-29 years. After menopause, bone mass loss is accelerated, and there is a period for old women in which the bone mass loss is accelerated again. Obviously, menopause and age are the dominant factors of OP. The sites of OP are in order of decreasing sensitivities as Ward's>Neck>Troch.
出处
《中国骨质疏松杂志》
CAS
CSCD
2005年第1期58-60,共3页
Chinese Journal of Osteoporosis
关键词
BMD
髋部
骨质疏松
OP
骨密度
筛查
调查
绝经后
年龄
女性
Hip bone
Bone mineral density
Osteoporosis
Healthy women
Dual-energy X ray absorptiometry
