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尖周病动物模型的时间评定 被引量:6

Time-evaluation of animal model of periapical diseases
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摘要 为了观察尖周病不同时间治疗结果的组织病理变化,必须建立尖周病动物模型。用35只恒河猴246牙的525个牙根研究证明:36、60、90d人工造成尖周病变率分别为41.67%、58.33%、96.88%。3个月、半年、1年尖周病疗效组织学愈合率分别为43.75%、58.80%、70.00%。表明人工造成尖周病变时间不能少于3个月,尖周病疗效观察时间至少1年以上,人牙临床疗效观察时间需要2年, The experimental study in 35 monkeies(525 dental roots) showed that the formation rates of artificial periapical diseases were 41.67%, 58.33% and 96.88% in the period of 36d, 60d, 90d respectively.After therapy, the examination revealed that the pathological cure rates of periapical diseases were 43.75%,58.80%, 70.00% in the period of 3, 6.12months respectively. The results suggested that the formation time for artificial periapical diseases was at least 3 months. The time for observing the treatment effect of periapical diseases of monkey should be at least 12 months. But the time for observing the clinical effects of the periapical diseases of human being should be the period of 2 years.
出处 《牙体牙髓牙周病学杂志》 CAS 1994年第1期5-6,共2页 Chinese Journal of Conservative Dentistry
关键词 动物模型 时间评定 根尖周围疾病 Periapical disease Animal model Time-evaluation.
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  • 1李卫东,王光华,肖明振.猴牙尖周病空管药物疗法的实验研究[J]实用口腔医学杂志,1986(01).

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