摘要
目的探讨颅脑损伤患者血清S鄄100B和神经元特异性烯醇化酶(NSE)的变化及其临床意义。方法用双抗体夹心ELISA法检测30名健康人和108例颅脑损伤患者血清S鄄100B和NSE水平。结果108例颅脑损伤患者在伤后12h血清S鄄100B水平[(1.24±0.32)滋g/L]较对照组[(0.38±0.12)滋g/L]升高,重型、中型和轻型颅脑外伤患者的血清NSE浓度均明显高于对照组的NSE浓度(P<0.01);而不同组别颅脑外伤患者血清NSE水平差异亦有显著性(P<0.05)。结论血清S鄄100B和NSE检测可作为诊断早期脑损伤的指标之一。
Objective To explore the changes of sera S-100B and neuron-specific enolase (NSE) and their significance in patients with brain injury. Methods Sera S-100B and NSE level of 30 healthy persons and 108 cases with brain injury were detected by ELISA method. Results The sera S-100B level of patient group increased after 12 h from brain injury, and sera NSE concentrations of severe type, middle type and minor type were significantly high than control group(P<0.01). However, sera NSE level of different types of brain injury also had significance(P<0.05). Conclusion Sera S-100B and NSE examinations can be used for diagnosis of early brain injury.
出处
《解剖学研究》
CAS
2005年第1期26-28,共3页
Anatomy Research
