摘要
目的探讨医院感染监控与治疗。方法对1993-2003年传染病院肝脏疾病患者,医院感染状况进行回 顾性分析。结果医院感染疾病,原发性细菌性腹膜炎居首,败血症其次,深部真菌感染发生率17％,肝衰竭患者 中发生率占32％,病死率高达82.1％;真菌性肺炎感染率是真菌感染的51.2％,病死率占94.7％;医院感染优势 病原菌,革兰阴性菌占60％-70％,大肠埃希菌居首占45.6％;真菌感染中白色念珠菌为主要菌占79％,曲霉菌 占13.1％;产超广谱β-内酰胺酶(ESBLs)细菌、凝固酶阴性葡萄球菌占85％,肠球菌属占40％,大肠埃希菌和肺 炎克雷伯菌分别为23.2％和23.8％。结论 医院感染危及生命、病死率最高是真菌性肺炎和真菌性败血症;多 种耐药细菌警示,产超广谱β-内酰胺酶(ESBLs)细菌增多,耐药菌与抗生素管理监控和合理治疗是关键。
OBJECTIVE To discuss the control and treatment of nosocomial infection. METHODS We analyzed all the serious hepatitis cirrhosis patients in 1993-2003 in infectious hospital. RESULTS Among nosocomial infection diseases, the first was peritonitis, the next was septicemia. Morbidity of systemic fungal infection was 17%> hepatic failure was 32% , and its mortality was 82. 1%. Among fungal infections, fungal pneumonitis was about 51. 2% , mortality was 94. 7%. Candida albicans infection among fungi was about 79% , aspergillosis was about 13. 1%. Among main becteria of nosocomial infection, the first was Escherichia coli 45. 6%. Extended-spectrum BBBBBBB-lactamases (ESBLs)-producing bacteria, and coagulase-negative staphylococci (CNS) were 85%, Enterococcus were 40% , Klebsiella pneumoniae and Escherichia coli were about 23. 8% and 23. 2%. CONCLUSIONS Fungal peritonitis and septicemia of nosocomial infection are with the high death rates due to multi-resistant bacilli, to which we must pay more attention. Due to increase in ESBLs it is important to manage the antibiotic use and the multi-resistant bacteria survey in order to proper use of antimicrobial agents.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2005年第3期318-321,共4页
Chinese Journal of Nosocomiology
关键词
医院感染
重型肝炎
耐药细菌
治疗
Nosocomial infection
Severe hepatitis
Resistance bacteria
Treatment
