摘要
目的:探讨脑钠肽(BNP)对急性冠状动脉综合征(ACS)近期预后评价的价值.方法:使用Triage BNP干氏床旁快速检测方法对106例ACS患者入院1～3 d的BNP水平进行测量,随访1个月,分为存活组和死亡组.结果:①存活组和死亡组BNP水平差异有统计学意义(P<0.01); ②单因素分析表明:血BNP≥172 ng/L(中位数)和Killip分级Ⅱ级以上为1个月内心源性死亡的预测因素(均P<0.01 );③Logistic回归分析表明:吸烟和血BNP≥596 ng/L(75%百分位数)为1个月内心源性死亡的独立预测因素(OR=5.50,P<0.05;OR=21.19,P<0.01).结论:ACS患者血BNP水平与其近期预后相关.
Objective: To investigate the short-term prognostic value of B-type natriuretic peptide in patients with acute coronary syndromes(ACS). Method:A total of 106 patients with acute coronary syndrome,whose blood BNP concentrations were measured with Triage BNP test,within 13 days after onset of ischemia symptoms,were divided into 2 groups:the survival and the non-survival, according to the results of 1 mouth follow - up. Result:The blood BNP concentration in the non-survival was significantly higher than in the survival;univariate analysis showed that ,BNP (172 ng/L,median)and Killip class (Ⅱ Ⅳ) were prognostic factors of short-term cardiac death in patients with ACS(P< 0.01);Logistic regression analysis indicated that smoking and BNP(596 ng/L,75% percentile) were independent predictors of short-term cardiac death in patients with ACS (OR= 5.5, P< 0.05;OR= 21.19, P< 0.01).Conclusion:Blood BNP level was related to short-term prognosis in patients with ACS.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2005年第3期176-178,共3页
Journal of Clinical Cardiology
关键词
急性冠状动脉综合征
脑钠肽
预后
Acute coronary syndrome
B-type/Brain natriuretic peptide
Prognosis
