神经营养素家族在突触发育成熟过程中的作用
The Effects Neunotrophins taking in the Process of Growth and Mature of Synopsis
摘要
神经营养素家族 (neunotrophins ,NTs)是促进神经元存活和分化的一类重要神经营养因子。近些年来大量研究发现NTs在突触的发育、成熟过程中也起着一定的作用 ,故本文主要从NTs对突触的形态、结构、功能 ,突触传递等方面的影响来详细阐述。
出处
《农垦医学》
2004年第6期442-444,共3页
Journal of Nongken Medicine
参考文献20
-
1[1]Li HS, Xu Xz, Montell C. Activation of a TRPC3 - dependent cation current through the neurotrophin BDNF. Neuron, 1999,24(1): 261~73
-
2[2]Chao MV. Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat Rev Neurosci, 2003,4(4): 299 ~ 309
-
3[3]Misgeld T. Burgess RW. Lewis RM et al. Roles of neurotransmitter in synapse formation: development of neuromuscular junctions lacking choline acetyltransferase. Neuron ,2002,36(4) :635 ~ 48
-
4[4]Martinez A, Alcantara S, Burrell V et al. TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections[J]. Neurosci, 1998,18 (18): 7336 ~ 50
-
5[5]Alsina B, Vu T, Cohen - Cory S. Visualizing synapse formation in arborizing optic axons in vivo: dynamics and modulation by BDNF. Nat Neurosci, 2001,4( 11 ): 1093 ~ 101
-
6[6]Yamada MK, Nakanishi K, Ohba S et al. Brain - derived neurotrophic factor promotes the maturation of GABA ergic mechanisms in cultured hippocampal neurons[J]. Neurosci .2002,22(17) :7580 ~ 5
-
7[7]Huang ZJ, Kirkwood A, Pizzorusso T et al. BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex.Cell, 1999,98(6) :739 ~ 55
-
8[8]Vicario - Abejon C, Collin C, McKay RD et al. Neurotrophins induce formation of functional excitatory and inhipitory synapses between cultured hippocampal neurons[J]. Neurosci. 1998,18(18) :7256 ~ 71
-
9[9]Mozhayeva MC,Sara Y,Liu X et al. Development of vesicle pools during mat uration of hippocampal synapses [ J ]. Neurosci, 2002,22 (3): 654 ~ 65
-
10[10]Collin C, Vicario - Abejon C, Rubio ME et al. Neurotrophins act at presynaptic terminals to activatesynapses among cultured hippocapal neurons[J]. Neurosci ,2001,13(7): 1273 ~ 82
-
1郭树章,任先军.神经营养素-3与脊髓损伤[J].中国矫形外科杂志,2005,13(10):776-777. 被引量:1
-
2朱永红,李海标.哺乳动物视网膜节细胞中神经营养因子的主要生物学作用[J].解剖学研究,2000,22(1):54-57. 被引量:1
-
3龚秸明,鲁凯伍,侯铁胜,李明.脊髓损伤基因治疗的研究进展[J].中国矫形外科杂志,2000,7(1):56-58. 被引量:3
-
4王存金,庞君,宋歌,李莉,曹俊平,张励才,王红军.钙黏蛋白在突触发育和突触可塑性调节中的作用[J].国际麻醉学与复苏杂志,2014,35(9):860-864.
-
5张虹,范婷婷.脑源性神经营养因子与临床疾病的新进展[J].上海医学,2007,30(11):877-880. 被引量:4
-
6邢仕歌,张英鸽.神经突触发育的影响因素及研究方法[J].中华神经医学杂志,2005,4(6):628-631. 被引量:2
-
7王堰婷,陆佩华.神经营养素与免疫细胞的关系[J].细胞与分子免疫学杂志,2001,17(1):95-97. 被引量:6
-
8郝建军,杨桂姣,高雨仁.脊髓损伤后神经营养素家族及其受体表达的研究进展[J].中国脊柱脊髓杂志,2007,17(7):549-551. 被引量:1
-
9王京,黄秉仁,田竞生.神经营养素-4及其受体的研究进展[J].医学研究杂志,1999,33(7):22-25.
-
10郭守刚,屈传强,杜怡峰,靳峰,王公明.双拷贝逆转录病毒载体介导的NT-3基因在嗅鞘细胞中的表达及其生物学活性[J].中华医学杂志,2009,89(9):638-640. 被引量:3