期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

谷氨酰胺强化的肠外营养在心肺联合移植中的应用 被引量：3

Glutamine supplemented parenteral nutrition in clinical heart-lung transplantation
下载PDF
导出
摘要 目的:探讨谷氨酰胺在心肺联合移植中的营养治疗作用. 方法:心肺联合移植术后,施行肠外和肠内营养支持,在肠外营养混合液中加入丙氨酰-谷氨酰胺(力肽)100～200 ml经深静脉输注. 结果:在长达6个月的肠外和肠内营养过程中,病人的肝功能、电解质和心功能均正常,移植的心脏活检和死亡后的病检均显示心内膜和心肌无病理改变,也无排斥反应表现. 结论:谷氨酰胺强化的肠外营养在心肺联合移植中具有营养治疗作用. Objective: To investigate therapeutic effectiveness of glutamine(Gln) in heart-lung transplanted patient. Methods: Parenteral nutrition(PN) and enteral nutrition (EN) were applied in a heart-lung transplanted patient, analyl-glutamine (Tipeptiven) 100-200 ml was added to total nutritional admixtures(TNA),and was transfused through deep vein. Results: The patient had received Gln supplemented nutritional therapy for 6 months, and the liver function、electrolyte and heart function were normal. Postgraft biopsy and autopsy didn , t show pathological changes of cardiac muscle and endocardium, and there was no rejection. Conclusions: Glutamine supplemented PN has nutritional and therapeutic effect in heart-lung transplantation patient.
作者 刘敦贵 曾凡军 周鸿敏 周绍棠 郭晖 陈忠华
机构地区 华中科技大学同济医学院器官移植研究所
出处 《肠外与肠内营养》 CAS 2005年第2期79-80,83,共3页 Parenteral & Enteral Nutrition
基金 卫生部<临床学科重点项目>卫规财发(2001)321号基金资助
关键词 联合移植 肠外营养 谷氨酰胺 营养治疗 肠内营养支持 深静脉 心内膜 结论 强化 过程 Heart-lung combined transplantation Glutamine Cardiac muscle
分类号 R459.3 [医药卫生—治疗学] R657 [医药卫生—外科学]
  • 相关文献

参考文献7

  • 1Dechelottep,Bleichner G,Hasselman M,et al.Improved clinical outcome in ICU patients receiving alanyl-glutamine(Depeptives) supplemented total parenteral nutrition(TPN)[J]. Clinical Nutrition,2002,21(1):1(abs).
  • 2Goeters C,Wenn A,Mertes N,et al.Parenteral L-alanyl-l-glutamine improves 6-month outcome in critically ill patients[J]. Crit Care Med,2002,30(4):2032-2037.
  • 3朱亮,李宁,李幼生,李元新,李维勤,朱维铭,刘放南,倪小东,曹斌,李为苏,罗开,黎介寿.肝肠联合移植术后的代谢调控治疗[J].肠外与肠内营养,2004,11(3):143-146. 被引量：5
  • 4Suleiman MS,Moffatt AC,Dihmis WC,et al.Effect of ischaemia and reperfusion on the intracellular concentration of taurine and glutamine in the heats of patients undergoing coronary artery surgery[J].Biochem Biophys Acta,1997,1324(2):223-231.
  • 5Khogli SE,Harper AA,Lyall JA,et al.Effects of L-glutamine on post-ischaemic cardiac function:protection and rescue[J]. J Moll Cell Cardiol,1998,30(4):819-827.
  • 6Cao Y,Kenned R,Klimberg VS.Glutamine protects against doxorubicin-induced cardiotoxicity[J].J Surg Res,1999,85(2):178-182.
  • 7Tamaki T,Konoeda Y,Yasuhara M,et al.Glutamine-induced heme oxygenase-1 protects intestines and heart from warm is-chemic injury[J].Transplant Proc,1999,31(6):1018-1019.

二级参考文献11

  • 1Hammarqvist F, Sandgren A, Andersson K et al. Growth hormone together with glutaminecontaining total parenteral nutrition maintains muscle glutamine levels and results in a less negative nitrogen balance after surgical trauma [J]. Surgery, 2001,129(5) :57
  • 2Berman RS, Harrison LE, Pearlstone DB et al. Growth hormone,alone and in combination with insulin, increases whole body and skeletal muscle protein kinetics in cancer patients after surgery [J]. Ann Surgery,1999,229(1):1-10.
  • 3Li YS, Li JS, Li N et al. Glycyl-glutamine-enriched long-term total parenteral nutrition attenuates bacterial translocation following small bowel transplantation in the pig[J]. J Surg Res, 1999,82(1):106-111.
  • 4Gondolesi G, Fishbein T, Chehade M et al. Serum citrulline is a potential marker for rejection of intestinal allografts [ J ]. Transplantation Proc, 2002,34(3) :918-920.
  • 5RothE, ValentiniL, SemsrothM et al. Resistance of nitrogen metabolism to growth hormone treatment in the early phase after injury patients with multiple injuries [J]. J Trauma, 1995,38 (1):136-141.
  • 6Shaw JH, Koea JB. Metabolic basis for the management of the septic surgical patient [ J ]. World J Surg, 1993,17 ( 2 ): 154-164.
  • 7Cao Y, Feng Z, Hoos A et al. Glutamine enhances gut glutathione production[J]. JPEN,1998,22(4) :224-227.
  • 8Rhoads JM, Argenzio RA, Chen W et al. L-Glutamine stimulates intestinal cell proliferation and activates mitogen-activated protein kinases[J]. Am J Physiol, 1997,272 (5): G943-953.
  • 9Harry T, Kevin O, Mark R et al. Glutamine deprivation induces apoptosis in intestinal epithelial cells [J]. Surgery, 1998,124(2): 152-159.
  • 10李幼生,黎介寿,李宁,李元新,刘放南.谷氨酰胺与谷氨酰胺双肽在小肠移植病人中的应用(附1例报告)[J].江苏医药,1998,24(8):565-566. 被引量：4

共引文献4

同被引文献98

引证文献3

二级引证文献7

肠外与肠内营养
2005年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部