摘要
目的研究妊娠妇女血清同型半胱氨酸(Hcy)、叶酸(FA)、维生素B12(VitB12)水平的变化及临床意义。方法检测35例正常妊娠、32例妊高征妇女以及20例正常非妊娠妇女的血清Hcy、FA、VitB12水平。结果妊娠妇女血清Hcy、FA、VitB12水平均显著低于非妊娠妇女(P<0.01)。妊高征患者血清Hcy水平显著增高,其血清FA、VitB12含量与正常妊娠妇女无显著性差异(P>0.05)。妊娠和妊高征组Hcy与血清FA、VitB12含量间均呈负相关。结论妊娠后妇女血清Hcy、FA、VitB12水平均显著降低(P<0.05-0.01),Hcy与FA、VitB12水平呈负相关;妊高征妇女血清Hcy水平显著高于正常非妊娠妇女;血清Hcy可能与妊高征的发生、发展密切相关。
Objective To study on the changes and clinical significance of serum homocysteineHcyfolic acidFAand Vitamin B12 levels in pregnant women. Methods The serum HcyFAand VitB12 levels were detected in 35 normal pregnant32 pregnant induced hypertension patients and 20 normal women. Results The serum Hcy FA and VitB12 levels in normal pregnant women were significantly lower than normal women p<0.01.The Hcy level in pregnancy induced hypertension patients increased significantly while FA VitB12 levels show no difference compared with normal pregnant women. Correlation analysis show that serum Hcy was negatively correlated with serum FA and VitB12 level in normal pregnant group and pregnant induced hypertension group. Conclusions Serum Hcy FA VitB12 level decreased significantly in pregnant womenP<0.05-0.01. Serum Hcy was negatively correlated with FA and VitB12 level in normal pregnant group and pregnant induced hypertension group. Serum Hcy may be an important risk factor for the development of pregnant induced hypertension.
出处
《海南医学》
CAS
2005年第5期3-4,共2页
Hainan Medical Journal
关键词
妊娠
妊高征
同型半胱氨酸
叶酸
维生素B12
pregnant
pregnant induced hypertensionPIH
homocysteineHcy
Vitamin B12VitB12 folic acidFA
