4Schindler, Christian W. JAK-STAT signaling in human disease[J]. The Journal of clinical Investigation ,2002,109(9) :1 133～1 137.
5Schaper F , Gendo C, Eck M, et al . Activation of the protein tyrosine phosphatase SHP2 Via the interleukin-6 signaltransducing receptor protein gp130 requires tyrosine kinase Jakl and limits acute-phase protein expression[J]. Biochem-J, 1998,335:557～565.
6Radaeva S, Jaruga B, Hong F , et al . Interferon-alpha activates multiple STAT signals and down-regulates c -Met in primary human hepatocytes[J]. Gastroenterology ,2002,122(4): 1 020～1 034.
7Bovolenta C, Pilotfi E, Mauri M et al. Human Fcell leukemia virus type 2 induces survival and proliferation of CD 34 (+) TF- 1 cells through activation of STAT1 and STATs by secretion ofinterferon- gamma and granulocyte macrophage- colony- stimulating factor[J]. Blood,2002,99(1) :224～231.
8Grandis JR, Drenning SD , Chakraborty A, et al . Requirement of stat3 but not stat1 activation for epidermal growth fact or receptor-mediated cell growth in vitro[J].J-clin -Invest, 1998,102(7): 1 385～1 392.
9Bromberg J F ,Fan Z, Brown C, et al. Epidermal growth factor induced growth inhibition requires statl activation [J]. Cell-Growth-Differ , 1998, (7) :505～512.
10Del'r Albani p, kahn MA ,Cole R,et al. ligodendroglial survival factors , PDGF-AA and CNTF, activate similar Jak/STAT signaling pathways [J]. J - Neurosci -Res , 1998,54(2):191～205.
