摘要
目的: 探讨自体带血运的肺组织瓣修补胸内食管不规则缺损的手术新方法,为临床应用提供动物实验依据。方法: 将14只实验犬的胸内食管行不同侧面的不规则切除,缺损面用自体带血运的肺组织瓣修补。观察其存活、进食情况以及愈合过程。结果: 3只犬术后1周内死亡, 11例存活,最长存活时间超过110周。存活犬食管缺损处的管腔表面可见新生的黏膜上皮爬覆。存活犬均能经口进食。结论: 应用自体肺组织瓣修补胸内食管不规则缺损可作为一种简便易行的新术式。
Objective: To investigate the feasibility to repair the intrathoracic irregular esophageal defect using pulmonary tissue flap with vascular pedicle for the future clinical application. Methods: Fourteen adult mongrel dogs were used for the study. An irregular full-thickness defect of different sides of intrathoracic esophageal wall was created, which was 3 to 6 cm long and 1/2 circled esophageal wall. The defect was patched by pulmonary tissue with vascular pedicle. Results: Three dogs died within 1 week after operation. Eleven dogs survived. One dog is still alive without problems for more than 110 weeks. The living dogs could be fed orally at the 7th day after operation. Epithelization was found in the luminal surface of the defect. Beneath it, fibrous tissue was observed. Conclusion: It would be a new surgical technique that the irregular esophageal defect was replaced by pulmonary tissue with vascular pedicle.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2005年第2期127-128,131,共3页
Journal of China Medical University
基金
卫生部科技专项立项项目(WKZ 2000 1 17)
关键词
肺组织瓣
食管缺损
食管重建
pulmonary tissue flap
esophageal defect
esophageal reconstruction
