摘要
目的进一步评价蒲参胶囊治疗原发性高脂血症的临床疗效。方法多中心随机平行对照临床试验。448例原发性高脂血症患者被随机分为两组:治疗组336例,服用蒲参胶囊;对照组112例,服用脂必妥片;两组疗程均为4周。主要疗效指标为总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL C)和高度脂蛋白(HDL C)。结果蒲参胶囊能使TC平均降低0.6246mmol/L,TG平均降低1.5343mmol/L,LDL C平均降低0.5764mmol/L,HDL C平均升高0.4406mmol/L;其中蒲参胶囊降低TG的疗效优于对照组(P<0.005)。结论蒲参胶囊对原发性高脂血症患者(尤其是TG升高者)有较好的调脂作用。
Objective To evaluate further the curative effect of Pushen Capsules on primary hyperlipidemia.Method The clinical test of multicentric random parallel control was used. The patients (n=448) were divided randomly into the treatment group (n=336) given Pushen Capsules and the control group (n=112) given Zhibituo Tablets. Two groups were all treated for 4 weeks. The main indexes of curative effect were TC, TG, LDL-C and HDL-C. Result Pushen Capsules could decrease averagely the level of TC to 0.6246mmol/L, TG, to 1.5343mmol/L, LDL-C, to 0.5764mmol/L and HDL-C, to 0.4406mmol/L. Pushen Capsules had a better curative effect to decrease the level of TG in the treatment group than that in the control group.Conclusion Pushen Capsules has a lipid-regulating function for the patient with primary hyperlipidemia especially with a higher level of TG.
出处
《北京中医药大学学报》
CAS
CSCD
北大核心
2005年第2期80-82,共3页
Journal of Beijing University of Traditional Chinese Medicine
关键词
蒲参胶囊
高脂血症
临床试验
Pushen Capsules
primary hyperlipidemia
clinical test
