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老年人颅脑外伤并发多器官功能衰竭的临床分析 被引量:15

Clinical features of multiple organ failure in the elder with craniocerebral trauma
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摘要 目的探讨老年颅脑外伤并发多器官功能衰竭(MOF)患者的进展和特点,分析其发病机制及防治措施。方法应用回顾性调查法分析36例MOF患者的临床特征、治疗方法及结果。结果36例MOF发生于外伤后平均5d;2、3、4个以上器官衰竭者死亡率分别为52.6%、58.3%、90%;器官衰竭发生顺序依次为:肺、胃肠道、肾、心血管、代谢、血液、免疫系统。结论肺部感染是老年颅脑外伤并发MOF最常见的诱因,及时采用预防保护措施可降低老年颅脑外伤患者的致残率、致死率。 Objective To investigate the clinical progress and characteristics of the craniocerebral trauma complicated by multiple organ failure (MOF) in the elder in order to find out its pathogenesis and therapeutic methods. Methods A retrospective analysis was conducted on clinical characteristics and therapy of 36 elderly patients with MOF. Results The 36 elderly patients developed MOF in average 5 d after craniocerebral trauma. The mortality rates were 52.6%, 58.3%, 90% in the patients with 2, 3, 4 or more than 4 failure organs. The lung was the first failing organ. Conclusion The major precipitating factor was infection and the commonest was pneumonia. Early observation and prevention are essential for reducing mortality and morbidity of elderly patients with MOF.
出处 《中华神经医学杂志》 CAS CSCD 2005年第4期380-382,共3页 Chinese Journal of Neuromedicine
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