摘要
【目的】研究爱西特与中药灌肠联合治疗慢性肾功能衰竭的疗效。【方法】选择慢性肾衰竭氮质血症期患者94例,肾衰竭期患者95例。氮质血症期患者随机分为A、B、C三组;肾衰竭期患者随机分为D、E、F三组。A、D组予爱西特口服,B、E组用中药灌肠,C、F组爱西特口服配合中药灌肠。观察各组治疗前后血清尿素氮(BUN)、肌酐(SCr)和内生肌酐清除率(CCr)水平及病情变化。【结果】①六组患者治疗后BUN、SCr均较治疗前显著下降,CCr均显著升高;②爱西特口服配合中药灌肠组较单用爱西特口服组或中药灌肠组肾功能指标改善更显著。【结论】爱西特与中药灌肠联合治疗慢性肾衰竭对于改善肾功能,延缓病情疗效肯定;其疗效优于单用爱西特或中药灌肠;此方法简便易行,价格低廉,适宜推广。
To study the therapeutic effect of Ai Xi Te combined with coloclysis of Chinese crude drug on treating chronic renal failure.Ninety-four patients with chronic renal failure in azotemia stage were divided into A、B、C groups randomly.Ninety five patients with chronic renal failure in renal failure stage were divided into D、E、F groups randomly.Group A and Group D were treated with Ai Xi Te by mouth, Group B and Group E were treated with retention enema of Chinese crude drug, Group C and Group F were treated with both Ai Xi Te by mouth and retention enema of Chinese crude drug. The levels of BUN, SCr and CCr in all patients were measured before and after therapy,as well as the changes of all patients' condition observed.①The concentrations of BUN and SCr in six groups after therapy significantly descended than those before therapy, while the level of CCr after therapy significantly heightened than that before therapy; ②The renal function parametes of the groups treated with both Ai Xi Te by mouth and retention enema of Chinese crude drug got more improvement than the groups treated with Ai Xi Te alone or treated with coloclysis of Chinese crude drug only.[Conclusion]The therapy of Ai Xi Te combined with coloclysis of Chinese crude drug for chronic renal failure is effective to improve the renal function and delay the pathogenesis of patients.The therapeutic effect of combined treatments for chronic renal failure is better than each treatment alone.This method is so convenient that it can be carried out easily and its price is cheap,therefore it is suitable to spread.
出处
《医学临床研究》
CAS
2005年第4期471-473,共3页
Journal of Clinical Research
