摘要
目的:研究慢性湿疹及慢性荨麻疹患者血清胃泌素的变化及其临床意义。方法:应用放射免疫分析测定63例慢性湿疹及37例慢性荨麻疹患者血清胃泌素水平, 43例年龄、性别相匹配的健康志愿者作为正常对照。结果:慢性湿疹组、慢性麻荨疹组与正常对照组血清胃泌素水平分别为(102 95±27 33)ng/L、(109 87±33 64)ng/L和(61 72±20 38)ng/L。经统计学分析,两疾病组与对照组之间均有显著性差异(P<0 01,P<0 01),而两疾病组之间无明显差异(P>0 05)。结论:慢性湿疹及慢性荨麻疹患者血清中胃泌素水平均增高,为临床治疗提供一定的指导意义。
Objective To study the clinical significance of changes of serum levels of gastrin in patients with chronic eczema or chronic urticaria. Methods Serum gastrin levels were, 37 patients with chromic urticaria and 43 controls. Results Serum gastrin levels in patients with chronic exzema (102.95±27.33ng/L) and patients with chronic urticaria (109.87±33.64ng/L) were both significantly higher than those in controls (61.72±20.38ng/L, both P<0.01). Difference between the levels in the two patients groups was not significant. Conclusion The high gastrin levels in those patients might reflect the presence of helicobacter pylori infections; eradication of which might be helpful for treatment of these chronic dermatologic disorders.
出处
《放射免疫学杂志》
CAS
2005年第2期85-86,共2页
Journal of Radioimmanology
