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常规治疗与合用帕罗西汀治疗功能性消化不良伴抑郁焦虑障碍的临床疗效观察 被引量:9

Observation of Therapeutic Effects of the Conventional Therapy and the Conventional Therapy Plus Paroxetine in the Treatment of Functional Dyspepsia with Depression and Anxiety Disorder
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摘要 目的:观察常规治疗与合用帕罗西汀治疗功能性消化不良(FD)伴抑郁焦虑障碍的临床疗效。方法:将82例FD伴抑郁焦虑障碍患者随机分为常规治疗(常规组)和抗抑郁药+常规治疗(抗抑郁组) ,疗程均为4wk ,观察治疗前、后FD症状评分及汉密顿抑郁量表(HAMD)、Zung抑郁自评量表(SDS)、焦虑自评量表(SAS)评分变化。结果:女性患者占81.7 % ,显著多于男性的18. 3 %(P<0 .01) ;治疗后抗抑郁组各项评分均显著下降(P<0 .01) ,而常规组则无明显改变(P>0. 05) ;抗抑郁组FD疗效及HAMD、SAS评分达常模范围的疗效与常规组比较有显著性差异(P<0. 01)。结论:常规治疗合用帕罗西汀,既能显著改善FD症状,又能有效控制抑郁焦虑障碍。 OBJECTIVE:To observe the therapeutic effects of the conventional therapy and the conventional therapy plus paroxetine in the treatment of functional dyspepsia(FD)with depression and anxiety disorder.METHODS:82cases of FD with depression and anxiety disorder were randomly divided into conventional therapy group and the conventional therapy plus paroxetine group(antidepressant group),both of which were subjected to4weeks treatment.scores of FD symptoms,HAMD,Zung SDS and SAS were observed both before and after treatment.RESULTS:The female cases accounted for81.7%,which significantly surpassed the males cases that accounted for only18.3%(P<0.01);after treatment,the scores of each item in antidepressant group decreased significantly(P<0.01),while no significant change was found in the conventional group(P>0.05);The therapeutic effect against FD symptoms,scores of HAMD and SAS meet the therapeutic effect in the norm range,which had a significant difference compared with the conventional group(P<0.01).CONCLUTION:Conventional therapy plus paroxetine can improve the symptoms of FD and control the depression and anxiety disorder effectively.
出处 《中国药房》 CAS CSCD 北大核心 2005年第8期612-614,共3页 China Pharmacy
关键词 常规治疗 帕罗西汀 功能性消化不良 抑郁焦虑障碍 Conventional therapy Paroxetine Functional dyspepsia Depression and anxiety disorder
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  • 1王宝恩,梁晓梅,贾博琦,陈宝雯,柯美云,林三仁,丁士刚,张锦坤,施礼,张志宏,陈隆典,徐家裕,袁耀宗,阮美娟,刘厚钰,邱德凯,张达荣,李增烈,欧阳钦,王一平,李瑜元,吴惠生,胡家露,姜若兰,王莜如,梁有信.西沙必利治疗功能性消化不良的多中心临床疗效观察[J].中华内科杂志,1995,34(3):180-184. 被引量:112
  • 2汪鸿志,江华.消化不良的临床与分型[J].中国实用内科杂志,1995,15(1):9-10. 被引量:129
  • 3吴文源.焦虑自评量表SAS[J].上海精神医学,1990,2:44-44.
  • 4王春芳.抑郁自评量表对1340例正常人评定分析[J].中国神经精神疾病杂志,1986,12(5):267-267.
  • 5李增裂.消化不良和临床流行病学[J].中国实用内科杂志,1995,15:5-6.
  • 6李增烈,中国实用内科杂志,1995年,15卷,5页
  • 7李瑜元,国外医学.内科学分册,1998年,25卷,105页
  • 8Masanori Handa,Kazunori Mine,Hiroshi Yamamoto,Shinichi Tsutsui,Haruo Hayashi,Naoko Kinukawa,Chiharu Kubo. Esophageal Motility and Psychiatric Factors in Functional Dyspepsia Patients with or Without Pain[J] 1999,Digestive Diseases and Sciences(10):2094~2098
  • 9Dr. Ingvard Wilhelmsen MD,Tone Tangen Haug MD,Holger Ursin MD,Arnold Berstad MD. Discriminant analysis of factors distinguishing patients with functional dyspepsia from patients with duodenal ulcer[J] 1995,Digestive Diseases and Sciences(5):1105~1111
  • 10Dr Douglas A. Drossman MD,Zhiming Li MD,Eileen Andruzzi,Robert D. Temple PhD,Nicholas J. Talley MD,W. Grant Thompson MD,William E. Whitehead PhD,Josef Janssens MD,Peter Funch-Jensen MD,Enrico Corazziari MD,Joel E. Richter MD,Gary G. Koch PhD. U. S. Householder survey of functional gastrointestinal disorders[J] 1993,Digestive Diseases and Sciences(9):1569~1580

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