摘要
目的研究麻醉诱导前扩容对腹腔镜手术后恶心呕吐(PONV)发生率的影响。方法80例择期行腹腔镜胆囊切除术患者随机分为两组:Ⅰ组在麻醉诱导前20min内,静脉输注15mL/kg乳酸林格氏液;Ⅱ组则给予2mL/kg的乳酸林格氏液;诱导后两组病人输液管理相同。分别记录两组病人术前、诱导时和手术开始后1、5、10min以及术毕时血压,比较补液量、麻醉药用量和麻醉时间,观察术后24h内恶心、呕吐发生情况。结果诱导时两组病人收缩压均较术前有所下降(P<0.05),且以Ⅱ组更为显著(P<0.05);Ⅰ组诱导前补液量明显多于Ⅱ组(P<0.05);病人PONV发生率Ⅰ组(22.5%)显著低于Ⅱ组(45%)(P<0.05)。结论麻醉诱导前扩容是一种降低PONV发生率的安全和有效的措施。
Objective To investigate the effects of volume expansion before induction of anaesthesia on postoperative nausea and vomiting(PONV) in patients undergoing laparoscopic operations. Methods Eighty patients sche- duled for laparoscopic cholecystectomy were enrolled in this study. Patients were randomly assigned to two groups: group Ⅰ, assigned to volume expansion management, were given an infusion of 15 mL/kg Ringer’s solution in 20 min before induction of anaesthesia, and group Ⅱ,patients were given an infusion of 2 mL/kg. After induction of anaethesia, fluid management was identical in both groups.The following index were recorded in each group: BP du- ring induction and 1, 5, 10 min after the beginning of operation and at the end of operation;duration of anaesthesia and usage of iv fluids and dosage of drugs,nausea and vomiting rate in the first postoperative day. Results The SBP during induction was significantly lower than that of other periods in each group. There was a significant diffe- rence in SBP during induction between the two groups. The incidence of PONV was significantly lower in group Ⅰ(22.5%)than that in group Ⅱ(45%)(P<0.05). Conclusion Volume expansion before induction of anaesthesia is safe and effective therapy for prevention of PONV.
出处
《上海第二医科大学学报》
CSCD
北大核心
2005年第4期412-414,共3页
Acta Universitatis Medicinalis Secondae Shanghai
关键词
麻醉诱导
扩容
腹腔镜手术
术后
恶心
呕吐
induction of anaesthesia
volume expansion
laparoscopic operation
postoperative narsea and vomiting
