1Li D, Friedman SI,, Liver fibrogenesis and the role of hepatic stellate cells: new insights and prospects for therapy J Gastroenterol Hepatol.1999, 14(7): 618-633.
2Bedossa P, Paradis V. Transforming growth factor-beta (TGF-beta) : a key role in liver fibrogenesis. J Hepatol, 1995. 22(2 Suppl):3742.
3Leivonen SK, Chantry A, Hakkinen L, et al. Smad3 mediates transforming growth factor-beta-induced collagenase-3 (matrix metalloproteinase13) expression in human gingival fibroblasts. Evidence for cross-talk between Smad3 and p38 signaling pathways, J Biol Chem, 2002, 277(48) : 46338 - 46346.
4Schnaper HW, Hayashida T, Hubchak SC. el al. TGF-beta signal transduction and mesangial cell fibrogenesis. Am J Physiol Renal Physiol.2003, 284(2): F243-252.
5Mariani TJ, Roby JD, Mecham RP, et al. Localization of type 1 procollagen gene expression in silica-induced granulomatous lung disease and implication of transforming growth factor-beta as a mediator of fibrosis.Am J Pathol, 1996, 148(1): 151-164.
6Keski-Oja J, Raghow R, Sawdey M, et al. Regulation of mRNAs for type-1 plasminogen activator inhibitor, fibronectin, and type 1 procollagen by transforming growth factor-beta. Divergent responses in lung fibroblasts and carcinoma cells. J Biol Chem, 1988,263 ( 7 ) : 3111-3115.
7Salo T, Lyons JG, Rahemtulla F, et al. Transforming growth factor-beta 1 up-regulates type Ⅳ collagenase expression in cultured human keratinocytes. J Biol Chem, 1991,266(18) : 11436-11441.
8Hall MC, Young DA, Water JG, et al. The comparative role of activator protein 1 and Smad factors in the regulation of Timp-1 and MMP-1 gene expression by transforming growth factor-beta1. J Biol Chem, 2003, 278(12) : 10304-10313.
9Friedman SL. Molecular mechanisms of hepatic fibrosis and principles of therapy. Gastroenterol, 1997, 32(3) : 424-430.
10Zagury D, Burny A, Gallo RC. Toward a new generation of vaccines:the anti-cytokine therapeutic vaccines. Proc Natl Acad Sci USA, 2001,98 (14) : 8024 -8029.
7Jie-Ting Tang,Jing-Yuan Fang,Wei-Qi Gu,et al. T celt immune re- sponse is correlated with fibrosis and inflammatory activity ira hepatitis B cirrhotics[J]. World Gastroenterol, 2010, 17 (9) : 3015-3019.
8Hammel P,Couvelard A, Otoole D,et al. Regression of liver fibrosis after biliary drainage in patients with chronic pancreatitis and stenosis of the common bile duct[J]. New England Journal, 2011,344 ( 19 ) : 418-423.
