摘要
目的探索化妆品生产车间空气尘埃粒子在不同时间、不同季节和不同生产车间的分布情况,对化妆品生产企业的GMP建立提供科学依据。方法选择广州市采用空气过滤净化系统的化妆品厂11家(以下简称净化厂)和非采用空气过滤净化系统的化妆品厂13家(以下简称非净化厂),分别在不同生产时间、不同季节和不同生产车间的情况下,分析车间空气中0.3、0.5、1、2、3、5μm尘埃粒子数的分布情况,评价其污染水平。结果净化厂和非净化厂在生产中均产生不同程度的尘埃粒子污染;净化厂空气中尘埃粒子在季节上基本无统计学意义,非净化厂季节上主要以中、大颗粒粒径尘埃粒子(1、2、3、5μm)有统计学意义,夏秋季高于冬春季;生产车间中净化厂以配制间、配料间和分装间产生的尘埃粒子浓度相对较高,非净化厂以配制、卫生通道、更衣室产生的尘埃粒子浓度相对较高。结论加强配制间、分装间和卫生通道的卫生管理,注意产品制作过程的密封工作,并改善制作和灌装设备;加强非净化厂生产过程的通风排气;制订洁净度标准,应不需考虑季节之分。
Objective To explore the distribution of airborne particles in cosmetic workshop in different periods, seasons and workshop, and to provide scientific foundation for the GMP establishment in cosmetic workshop. Methods Distribution of airborne particles of diameter of 0.3, 0.5, 1, 2, 3 and 5μm in workshops was determined and evaluated on contamination level in 11 cosmetic factories equipped with air purification system (APS) and 13 cosmetic factories without APS at different production period and seasons. Results The factories with APS and without APS in this study all had airborne particles to different degrees during producing process. The air particle pollutions in factories with APS had not statistical differences between different seasons. In factories without APS, air particles of medium and large diameters(1, 2, 3 and 5μm) were statistically more in summer and autumn than in winter and spring. In workshops of factories with APS, the air particle pollution was statistically more severe in preparation workshops, material workshops and packaging workshops. In workshops of factories without ADS, the air particle pollution was statistically more server in preparation workshops, sanitation passways and dressing rooms. Conclusions Rigorous hygienic supervision should be practiced in preparation workshops, packaging workshops and sanitation passways. Attention should be paid to the separation of production, especially the packing equipment, and to the ventilation in factories without APS. Cleanness standards should be strictly observed all the year round.
出处
《热带医学杂志》
CAS
2005年第1期67-70,共4页
Journal of Tropical Medicine
基金
广东省重点科技项目(No.2KM06402S)。
关键词
化妆品
尘埃粒子
粒径
季节
时间
cosmetic
particles
particle diameter
seasons
time
