摘要
目的 通过测定维持性透析患者血管通路血流量、Kt/V值及尿素清除率 (URR)的定量分析 ,进一步探讨血流量对透析充分性的影响。方法 本研究选择慢性维持性血液透析患者 80例。设定血液透析开始后在线血流量 ,根据血流量不同分为 3组 ,I组血流量 30 0ml/min ,Ⅱ组血流量 2 5 0ml/min ,Ⅲ组血流量2 0 0ml/min ,计算各组Kt/V值与尿素减少率 ,观察血流量与Kt/V值及尿素减少率之间的相关关系。结果 3组之间Kt/V、URR比较P <0 .0 0 1,差异均具有显著性 ;血流量与Kt/V、URR之间呈正相关 (r1=0 .4 4 8,P <0 .0 0 1;r2 =0 .4 13,P <0 .0 0 1;)随着血流量从 30 0ml/min降到 2 0 0ml/min ,Kt/V、URR分别从(1.33± 0 .33)、(6 8.19± 8.86 ) %降到 (0 .99± 0 .31)、(5 8.5 9± 13.19) % ,分别降低 2 5 .5 6 %、14 .0 8%。结论 进一步从定量水平明确血液透析患者的血流量与Kt/V、URR密切相关 ,透析时保证足够的血流量是透析患者综合临床状况分析的一项重要指标。
Objective To understand the effect of blood flows o n dialysis adequacy by measuring blood flow of access,Kt/V and urea reduction ra tio (URR) of maintenance hemodialysis patients. Methods The blood flow of access, Kt/V and URR at the beginning of one hemodialysis session were observed and calculated. The relationship betwe en the blood flow of access and Kt/V and URR were analyzed. Results We found that there was a significant positive correla tion between the blood flow of access and Kt/V and URR (r1=0.448, P<0.00 1; r2=0.413,P<0.001 respectively). As the blood flow red uced from 300 ml/min to 200 ml/min, Kt/V and URR reduced from 1.33±0.33、(68.19 ±8.86)% to 0.99±0.31、(58.59±13.19)% respectively, reduced 25.56%、14.08%. Conclusion The blood flow of access of the chronic maintenance hemodialysis patients is a valuable index of the hemodialysis quality.
出处
《中国血液净化》
2005年第1期14-15,51,共3页
Chinese Journal of Blood Purification
关键词
维持性血液透析
KT/V
血流量
尿素减少率
Maintenance hemodialysis
Kt/V
Blood flowed volume
Urea reduction ratio (URR)
