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Syk基因启动子甲基化与肿瘤 被引量:1

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作者 傅平 曾庆黎
出处 《实用临床医学(江西)》 CAS 2005年第4期135-137,共3页 Practical Clinical Medicine
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  • 1Watanabe Y. Expression of tyrosine kinase Syk in pancreatic cancers. Hokkaido Igaku Zasshi,2001,76(3) : 173 - 81.
  • 2Kiyonao S, Tomoko T, Shigeru Y,et al. Structure and Function of Syk Protein - Tyrosine Kinase. J Biochem 2001, 130, 177 -186.
  • 3Toyama T, Iwase H, Yamashita H,et al. Reduced expression of the Syk gene is correlated with poor prognosis in human breast cancer. Cancer Lett 2003 ,189(1) :97 - 102.
  • 4Stewart Z, Pietenpol J. Syk: a new player in the field of breast cancer. Breast Cancer Res 2001,3(1):5 - 7.
  • 5Murphy M, Schnall R, Venter D, et al. Tissue hyperplasia and enhanced T- cell signalling via ZAP- 70 in c - Cb1- defucuebt mice. Mol. Cell. Biol. 1998,18, 4872-4882.
  • 6Coopman J, Do M, Batth M, et al. The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells, Nature 2000,406:742-747.
  • 7Ganapati H, Mahabeleshwar, Gopal C. SYK, a protein tyrosine kinase suppresses the cell motility and nuclear factor kB mediated secretion of urokinase type plasminogen activator by inhibiting the phosphatidylinositol 3' - kinase activity in breast cancer cells. J Biol Chem 2003,278:6209 - 6221.
  • 8Yuan, R. Mendez, A. Sahin, J. Hypermethylation leads to silencing of the Syk gene in human breast cancer, Cancer Res.2001, 61:5558- 5561.
  • 9Yong-Bin Ding Guo-Yu Chen Jian-Guo Xia Xi-Wei Zang Hong-Yu Yang Li Yang Department of General Surgery,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,Jiangsu Province,China.Association of VCAM-1 overexpression with oncogenesis,tumor angiogenesis and metastasis of gastric carcinoma[J].World Journal of Gastroenterology,2003,9(7):1409-1414. 被引量:26

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