摘要
目的:通过对使用抗生素序贯疗法治疗儿童下呼吸道感染的疗效观察,分析其在儿童下呼吸道感染,尤其是在基层医院应用的可行性.方法:临床诊断为细菌性下呼吸道感染的所有病例,入院后均给予青霉素类或头孢菌素类抗生素药物静脉滴注及对症治疗.观察组60例病儿静脉用药3～5d,待临床症状及体征明显改善后改为同类型的口服抗生素.治疗组30例静脉持续用药.两组总疗程均为7～10 d.结果:使用抗生素序贯疗法的观察组与应用常规疗程的对照组比较在治疗疗效上无统计学差异,而在住院天数及医疗费用支出方面却明显优于对照组.结论:使用抗生素序贯疗法治疗儿童下呼吸道感染一方面可减轻患儿的痛苦、减少住院时间、减少局部感染及院内交叉感染发生的机会;另一方面可降低医疗费用及减轻家长的经济负担.该方法对患儿及家长、医务人员及社会均有益,特别是在基层及广大农村,治疗疾病的费用有限,序贯疗法可促进有限的医疗资源更充分合理的应用,值得在儿科临床推广.
Objective: To observe the effectiveness and the feasibility of antibiotic sequential therapy for children′s lower respiratory tract infection, especially in Primary hospital.Methods: All the patients with bacterial lower respiratory tract infection were received penicilin or cephem antibiotics by intervenou drop infusion and symptomatic treatment.In the observation group, 60 children were treated by intervenous drop infusion for three to five days, then altered for oral antibiotics of the same kind after their clinical symptom and physical sign were improved remarkably. In contrast,the treatment group, 30 children were treated by intervenous drop infusion continously.The total duration of treatment for both groups were seven to ten days. Results: There was no difference between the two groups about therapeutic effect; However, the hospitalization days and medical cost of the observation group were obviously higher than that of teratment group. Conclusion:On one hand, antibiotic sequential therapy can relieve the children′s suffering, shorten the hospitialization time, decrease the opportunity of local infection and cross infection. On the other hand, it can make medical cost lower, relieve their parent′s burden. The method can benefit all the patients, medical staff and our society,especially in basic level and countryside. Since the expense of treating disease is limited in primary hospitals, sequential therapy can promote better use of medical resources,and it′s worthwhile to spread in paediatrics′clinical.
出处
《中国临床医学》
北大核心
2005年第2期347-348,共2页
Chinese Journal of Clinical Medicine
