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猪囊尾蚴病的小鼠动物模型的建立 被引量:11

ESTABLISHMENT OF MOUSE MODEL FOR CYSTICERCOSIS CELLULOSAE
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摘要 对猪带绦虫病患者,用南瓜子、槟榔和50%硫酸镁驱虫。成虫漂洗后取成熟孕节分离虫卵。虫卵于培养瓶内,加入人胃液、猪胆汁、胰酶等,置于37℃温箱孵化,再将孵出的六钩蚴注入昆明种小鼠尾静脉内,感染2个月后解剖,在其肌肉和肺脏检出活猪囊尾蚴。将囊尾蚴置于胃液和胆汁中,于37℃孵化2h,其头节可自动翻出。 Sixty mice were inoculated intravenously with 200-400 Taenia solium eggs collectedfrom the gravid proglottides of the adult worm expelled from a taeniasis patient after pump-kin seed and areca treatment.The mice were killed and dissected 2 months after inoculation,and were found infected with Cysticercus cellulosae,These living cysticerci in muscles andlungs were elliptic in shape with diameters of 0.3-0.6cm. The scolex was equipped withtwo rows of hooks and four typical suckers When the cysticerci were hatched in gastric juiceand bile for two hours at 37℃ the scoleces evaginated volutarily.The resuIts of this studysuggest that the mouse can be used as an animal model for Cysticercus cellulosae.
出处 《中国寄生虫学与寄生虫病杂志》 CAS CSCD 北大核心 1994年第4期297-299,共3页 Chinese Journal of Parasitology and Parasitic Diseases
关键词 猪囊尾蚴 人工感染 动物模型 囊尾蚴病 Taenia solium,Cysticercus cellulosae,egg hatching,artificial infection,animal model
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