摘要
本文观察描述１００例经病理检验、弓形虫抗原与抗体检测、弓形虫株分离而诊断为弓形虫病宫内感染胎婴儿的病理学变化。认为见到下述病变时，应在组织切片中查找弓形虫：脑或其它各器官组织切片中见到钙化灶；血管损伤及其相关的病变；各器官组织切片中见有嗜酸粒细胞浸润；脑小胶质细胞及组织中小淋巴细胞的核淡染或空染；游离的弓形虫滋养体因大小及形态多样散在分布于组织中极似坏死性炎时崩解的核碎屑，但无嗜中性粒细胞浸润及脓细胞的图象。各器官肉眼观察未见病灶时，并不能否定弓形虫感染的存在，因机体已有免疫能力之故。
Pathological changes of 100 cases of fetus-infant congenital toxoplasmosis diag-nosed by pathological examination,determination of Toxoplasma antigen and antibody, isolationof Toxoplasma strain,are described.It is considered that if pathological changes described beloware seen,the histopathological sections have to be examined for Toxoplasma :calcification of brainand other organs,injury of blood vesseles and their relative pathological changes,eosinophil infil-tration in organs,staining-fast or staining-thin of nuclei of glial cells of brain and microlym-phocytes in tissues. Because they are changeable in size and shape,free Toxoplasma trophozoitesscattered in tissues are much more similar to debris of nuclei crumbled in necrotic inflammation,but there are no polymorphonuclear infiltration and pus cells.The diagnosis of congenital toxo-plasmosis could not be excluded when no specific pathological changes are found by naked eyes,because the immunity might have been developed.
出处
《中国寄生虫病防治杂志》
CSCD
1994年第3期209-212,共4页
Chinese Journal of Parasitic Disease Control
基金
江苏省科委社会发展项目
关键词
弓形体病
妊娠感染
胎儿
婴儿
Toxoplasma infection fetus-infant pathological morphology
