期刊文献+

医学生物信息学在心血管研究领域的应用——数据与知识 被引量:2

The Application of Biomed-Informatics in Cardiovascular Research——Data and Knowledge
下载PDF
导出
摘要 随着生物技术的进步,特别是以基因组、蛋白质组为标志的导致高通量实验数据产生的工作的开展,大量的实验数据在各个领域堆积拥塞,与领域内的知识的累计出现了极为不平衡的发展,因此,对这些数据的处理成为了学科发展的迫切需求。为了避免这些数据成为垃圾,数据库、统计学、信号处理、数据挖掘、知识管理、人工智能等多种技术被运用到医学生物学领域,使得医学生物信息学不再是医学、生物学和信息学、计算机科学的单纯交叉,而独立成为一门专业的学科,重点也由原来单纯的研究计算机信息技术在医学生物信息学中的延展和运用,转变到研究、发现、开发、创新适合医学生物学自身特点的新思想和新方法上来[1, 2]。本文对近年来心血管领域内医学生物信息发展和运用的情况进行了回顾和分析,并对该领域可能的发展方向做出判断。 With the development of biotechnology, especially the projects which lead to high throughout experimental results, lots of data have been jammed in every related fields, and broke the balance between data and knowledge in these fields. It is urgent to refine these data, and let them be more productive. To avoid these data being decaying into rubbish, technology and theory such as database, statistics, data mining, knowledge management, and artificial intelligence had been applied into biologic and medical study fields. So, a new standalone research subject - biomed-infomatics has been formed. This paper reviewed the application of biomed-informatics in cardiovascular research, and gave the view for the future development of this subject.
出处 《生理科学进展》 CAS CSCD 北大核心 2005年第2期119-124,共6页 Progress in Physiological Sciences
关键词 医学生物信息学 数据库 数据挖掘 知识管理 心血管学 Biomed-informatics Database Data mining Knowledge management Cardiovascular science
  • 相关文献

参考文献18

  • 1Concept of bioinformatics. http://otir.cancer.gov/tech/bioinformatics.html
  • 2Kapetanovic IM, Umar A, Khan J. Proceedings: The Applications of Bioinformatics in Cancer Detection Workshop. Ann NY Acad Sci, 2004,1020: 1~9.
  • 3Benson DA, Karsch-Mizrachi I, Lipman DJ, et al. GenBank. Nucleic Acids Res, 2002, 1:17~20.
  • 4Boeckmann B, Bairoch A, Apweiler R, et al. The Swiss-Prot protein knowledgebase and its supplement Trembl in 2003. Nucleic Acids Res, 2003, 1: 65~70.
  • 5Macleod MR. PubMed: http://www.pubmed.org. J Neurol Neurosurg Psychiatry, 2002, 73:746~752.
  • 6Peri S, Navarro JD, Amanchy R, et al. Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res, 2003, 13:2363~2371.
  • 7Zhang QP, Lu M, Shi L, et al. Cardio: a web-based knowledge resource of genes and proteins related to cardiovascular disease. Iin J Cardiol, 2004, 97: 245~254.
  • 8Shi L, Zhang Q, Rui W, et al. BioPD: a web-based information center for bioactive peptides. Regul Pept, 2004, 120:1~3.
  • 9Bober M, Wiehe K, Yung C, et al. CaGE: cardiac gene expression knowledgebase. Bioinformatics, 2002, 18:1013~1014.
  • 10Pleissner KP, Sander S, Oswald H, et al. The construction of the World Wide Web-accessible myocardial two-dimensional gel electrophoresis protein database "HEART-2DPAGE": a practical approach. Electrophoresis. 1996, 17:1386~1392.

同被引文献16

引证文献2

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部