摘要
选用阿苯达唑３００ｍｇ伍用复方甲苯达唑３７５ｍｇ１．５ｄ联合疗法分别治疗蛔虫感染者７例、鞭虫感染者７例和钩虫感染者９例。治后３ｄ内粪检蛔虫卵全部转阴，鞭虫卵和钩虫卵亦于治后５ｄ内全部转阴。连续粪便培养发现，治后虫卵发育率较治前明显降低，治后２ｄ对蛔虫、鞭虫和钩虫的杀卵率分别达９８．８％、１００％和１００％。研究结果表明，联合化疗具较强的体内驱虫杀卵作用。
The effect of a combination of albendazole and mebendazol was evaluated by stool exa mination in 7 patients with Ascaris lumbricoides eggs,7 patients with Trichuris trichiura eggs and 9 patients with hookworm eggs.Albendazole and mebendazole were given at 300 mg and 375 mg,respectively.Both drugs were divided into 3 parts, one part b.id., and given in 1.5 days.The fecal eggs turned negative in all the patients with Ascaris infection in 3 days,while the fecal eggs were negative in all patients with Trichuris or hookworm infection in 5 days.The development rates of the eggs were remarkably lower post treatment than pre treatment.It was found that the ovicidal rates in human ascariasis,trichuriasis and ancylostomiasis were 98.8% ,100% and 100%,respectively on the second day following the initiation of treatment.The results showed that the worm repelling and ovicidal effect of the combined chemotherapy was more evident.
出处
《中国寄生虫学与寄生虫病杂志》
CAS
CSCD
北大核心
1994年第1期52-55,共4页
Chinese Journal of Parasitology and Parasitic Diseases
基金
江苏省自然科学基金
关键词
阿苯达唑
甲苯达唑
蛔虫病
鞭虫病
Albendazole,mebendazole,chemotherapy,ascariasis,trichuriasis,ancylostomiasis
