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Endoglin与动脉粥样硬化

Role of Endoglin in Atherosclerosis
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摘要 Endoglin(CD105)是转化生长因子-β的一种结合蛋白,可通过影响转化生长因子-β的信号传导而发挥作用。Endoglin在血管细胞的分布及其生理作用对动脉粥样硬化的发生发展起到一定的作用。 Endoglin(CD105)is an endothelial membrane glycoprotein involved in cardiovascular morphogenesis and vascular remodeling.It associates with transforming growth factor-β(TGF-β)signaling receptors to bind TGF-β family members,forming a functional receptor complex.Endoglin plays roles in the process of atherosclerosis.
作者 梅卫义 杜志民 陈国伟
机构地区 中山大学附属第一医院心内科
出处 《心血管病学进展》 CAS 2005年第3期293-296,共4页 Advances in Cardiovascular Diseases
关键词 ENDOGLIN 动脉粥样硬化 转化生长因子-Β 结合蛋白 发挥作用 信号传导 发生发展 生理作用 血管细胞 Transforming growth factor-β Endoglin Atherosclerosis
分类号 R543.3 [医药卫生—心血管疾病]
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参考文献31

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心血管病学进展
2005年 第3期

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