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白三烯受体拮抗剂的作用机制及临床应用的研究进展 被引量:110

Mechanisms of action of cysteinyl leukotriene receptor antagonist and progresses in relevant studies in children with asthma
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作者 董琳
出处 《中华儿科杂志》 CAS CSCD 北大核心 2005年第4期266-268,共3页 Chinese Journal of Pediatrics
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  • 1Fregonese L, Silvestri M, Sabatini F, et al. Cysteinyl leukotrienes induce human eosinophil locomotion and adhesion molecule expression via a Cys-LTI receptor mediated mechanism. Clin Exp Allergy, 2002, 32: 745-750.
  • 2Braccioni F, Dorman SC, O′ byrne PM, et al. The effect of cysteinyl leukotrenes on growth of eosinophil proge from peripheral blood and bone marrow of atopic subjects. J Allergy Clin Immunol, 2002, 110:96-101.
  • 3Murray J, Ward c, O′ Flaberty JT, et al. Role of leukotrenes in the regulation of human granulecyte behaviour: dissociation between agonist-induced activation and retardation of apoptosis. Br J Pharmacol, 2003, 139:388-398.
  • 4Henderson WR Jr, Tang LO, Chu SJ, et al. A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model. Am J Respir Crit Care Med, 2002, 165:108-116.
  • 5Stelmach I, Jerzynska J, Kuna P. A randomized, double-blind trial of the effect of treatment with montelukast on bronchial hyperresponsiveness and serum ECP, sIL-2R, IL-4, and sICAM-1 in children with asthma. J Allergy Clin Immunol, 2002,109: 257-263.
  • 6Stelmach I, Grzelewski T, Stelmach W, et al. Effect of triamcinolone acetonide, montelukast, nedocromil sodium and formoterol on eosinophil blood counts, ECP serum levels and clinical progression of asthma in children. Pol Merkuriusz Lek, 2002,12:208-213.
  • 7Strauch E, Moske O, Thoma S, et al. A randomized controlled trial on the effect of montelukast on sputum eosinophil cationic protein in children with corticosteroid-dependent asthma. Pediatr Res, 2003, 54:198-203.
  • 8Diamant Z, Grootendorst DC, Veselic-Charvat M, et al. The effect of montelukast (MK-0476), a cysteinyl leukotriene receptor antagonist, on allergen-induced airway responses and sputum cell counts in asthma. Clin Exp Allergy, 1999, 29:42-51.
  • 9Wu AY, Chik SC, Chan AW, et al. Anti-inflammatory effects of high-dose montelukast in an animal model of acute asthma. Clin Exp Allergy, 2003, 33:359-366.
  • 10Finsnes F, Lyberg T, Christensen G, et al. Leukotriene antagonism reduces the generation of endothelin-1 and IFN-γand inhibits eosinophilic airway inflammation. Respir Med, 2002,96: 901-906.

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