摘要
目的:探讨胎膜早破母血中IL-8对足月产前绒毛膜羊膜炎的诊断价值。方法:采用放射免疫法对30例胎膜早破和20例正常足月孕妇血IL-8进行测定,组织绒毛膜羊膜炎通过产后胎盘病理证实。结果:轻度、中重度绒毛膜羊膜炎与非绒膜羊膜炎相比均有显著性差异(P<0.01),轻度与中重度相比差异无显著性。轻度、中重度与非绒毛膜羊膜炎组IL-8水平分别为1.1141ng/ml,1.3287ng/ml,0.8108ng/ml。结论:母血IL-8水平可作为足月胎膜早破组织绒毛膜羊膜炎的一个预测指标。
Objective: To study the diagnostic value of maternal serum interleukin-8 (IL-8) concentrations in patients with premature rupture of membranes (PROM) for chorioamnionitis atterm. Method: 30 pregnant women with PROM atterm and 20 normal pregnant women atterm were enrolled. Maternal serum IL-8 were measured by radioim-munoassay. Chorioamnionitis was histopathologically confirmed after delivery. Result: The serum of maternal IL-8 with histological chorioamnionitis showed a significant increased than those without chorioamnionitis (P<0.01). No significant differences in IL-8 levels were observed between the pregnant with mild and moderate chorioamnionitis. The level of serum IL-8 in mild stage (1.1141ng/ml). Moderate severes stage (1.3287ng/ml) and without chorio amnionitis (0.8108ng/ml). Conclusion: Measurement of maternal serum IL-8 is a marker for screening histological chorioamnionitis PROM atterm.
出处
《河北医学》
CAS
2005年第4期315-317,共3页
Hebei Medicine
关键词
胎膜早破
白细胞介素-8
产前诊断
绒毛膜羊膜炎
Premature rupture of membrane
Interleukin-8
Prenatal diagnose
Chorioamnionitis
