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小剂量红霉素治疗早产儿胃肠功能紊乱疗效观察 被引量:5

Study on Clinical Effect of Small Dose of Erythromycin for Preterm Infants with Gastrointentinal Dysfunction
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摘要 目的探讨小剂量红霉素治疗早产儿胃肠道功能紊乱的疗效。方法将符合诊断标准的69例患儿随机分为治疗组35例,对照组34例。治疗组在给予常规对症处理、支持治疗基础上加用小剂量红霉素3~5mg/(kg·d),缓慢静脉滴注,1次/d,连用7天。结果治疗组呕吐症状、胃肠潴留缓解及体重增长有效率分别为:77.1%、80.0%、74.3%。均高于对照组(P<0.05),具有明显的治疗作用。结论小剂量红霉素治疗早产儿胃肠道功能紊乱安全有效,具有一定的临床价值。 Objective To study the clinical effect of a small dose of erythromycin for the preterm infants with gastrointentinal dysfunction. Methods 69cases of gastrointentinal dysfunction were divided into two groups at random. Erythromycin group of 35 cases and control group 34 cases. The control group was treated routinely. Besides routine therapy, Erythromcin groups were treated with intraveous erythromycin slowly dropping at a low dose of 3~5mg/(kg.d). Once a day and for 7 days.Results The effect rate of Erythromycin groups higher than that of control group(P <0.05), in signs of vomiting mitigating(77.1%),stomach retention (80.0%)and weight growing( 74.3%).No significant adverse effects were observed. Conclusion Low dose of erythromycin administration in the preterm infants with gastrointantinal dysfunction is effective in clinical practice.
出处 《医药论坛杂志》 2005年第7期39-40,共2页 Journal of Medical Forum
关键词 早产儿 红霉素 胃肠功能紊乱 Preterm infant Erythromycin Gastrointentinal dysfunction
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  • 1张传继,丛培喜,毛学忠,曹洪贤,刘学兰.红霉素对糖尿病患者胃轻瘫的影响[J].中华消化杂志,1996,16(2):108-109. 被引量:7
  • 2相洪琴(译).-[J].国外医学情报,1998,19(10):42-42.
  • 3大野彰二 须贺达夫 等.-[J].日胸会志,1994,53(8):674-679.
  • 4Vandenplas Y. Oesophageal PH monitoring for gastrooesophageal reflux in infants and children. England: John Wiley &Sons, 1992,69 - 75.
  • 5Corrhaldesi R, Scarpingnato C, Callassi V, et al. Effects of ranitidine and cimetidine on gastric emptying of a mixted meal in man. Int J Clin Pharmacol Thera, 1984,22:498-501.
  • 6Feldman M, Herbert J, Feldman SM, et al. Effect of cisapride on gastric emptying of indigestible solig in patients with gastroparesis diabeicoum. Gastroenterology, 1987,92:171.
  • 7Sarna SK, kyan RP, Brandon A. Erythromycin acts on presynaptic neurons to stimulate gastrointestinal motor activity. Gastroenterology, 1991,100: A490.
  • 8Weber FH, Richards RD, Mc callam RM. Erythromycin. AS motilin agopnist and gastointsetinal Prokindtic agent. Gastroenterology, 1993,104:485.
  • 9金汉珍 黄德民 宫希吉 主编.实用新生儿学 第二版[M].北京:人民卫生出版社,1999.408—411.
  • 10方鹤松 魏承毓 段恕诚 等.腹泻病疗效判断标准的补充建议.中国实用儿科杂志,1998,13(6):384-384.

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