摘要
对424例急性疼痛病人,采用随机对照双盲法,观察单次给予丙氧氨酚片或安慰剂或氨酚待因片.三组病例统计结果表明,丙氧氨酚片的有效的镇痛效应率为 96.03%,安慰剂组为41.51%,氨酚待因组为81.16%.上述结果说明丙氧氨酚片在解除急性疼痛方面有较好的疗效.
424 volunteers with acute pain were selected and randomized into 3 drug groups. Eachof them received single dose of tablets of placebo, propoxyphene napsylate-acetaminophen or acetaminophen and codeine respectivily by means of double-blind method. On the basis of similar background in the three groups, we founded that the validity rate of the tested new drug, comparison groups and placebo groups were 96. 03%, 81. 16% and 41. 57% respectivily. The data mentioned above showed that propoxyphene napsylate-acetaminophen possessed good effect on relieving pain.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
1994年第3期148-152,共5页
The Chinese Journal of Clinical Pharmacology
关键词
丙氧氨酚片
Ⅱ期临床试验
急性疼痛
propoxyphene napsylate-acetaminophen
phase Ⅱ clinical trial
acute pain
