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酵母乳糖酶肠溶微囊制剂用于治疗乳糖不耐受大鼠的疗效观察 被引量:3

The Efficacy of Microencapsulated Lactase Therapy of Lactose- intolerant Adult Rats
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摘要 为观察用于治疗各种乳糖不耐受的酵母乳糖酶肠溶微囊制剂的疗效,本实验经筛选得四组乳糖不耐受成年雄性大鼠,经灌胃给予2g/kg·W剂量的乳糖,同时给予不同剂量的乳糖酶肠溶微囊制剂,并定时采血测定血糖.结果表明:18.7IU/kg·W的乳糖酶肠溶微囊制剂已能有效地促进乳糖不耐受大鼠对乳糖的消化和吸收. A study to determine the efficacy of microencapsulated lactase therapy of lactose intolerance was undertaken in 48 rats. The 48 lactose-intolerant adult rats were divided into four groups. Each group rats were given a load of 2 g per kg body weight lactose and a certain dose of microencapsulated lactase. Blood samples were collected before and 30, 60, 90, 120 min after the adminstration of lactose. Blood galactose concentration were determined as a level of lactose absorption. The results showed: a dose of 18. 7 IU per kg weight microencapsulated lactase can greatly increase the level of lactose absorption.
出处 《中国生化药物杂志》 CAS CSCD 1994年第3期186-190,共5页 Chinese Journal of Biochemical Pharmaceutics
基金 国家"七五"攻关课题
关键词 乳糖不耐受症 乳糖酶肠溶微襄 Lactose intolerance Microencapsulated lactase
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  • 1王宝西.小儿慢性腹泻并乳糖不耐受及其治疗对策[J].实用儿科临床杂志,2006,21(19):1286-1288. 被引量:21
  • 2王晖,张玲,王秀玲,黄涛,王丽君.婴幼儿腹泻与乳糖不耐受关系的研究[J].中国微生态学杂志,2007,19(2):222-222. 被引量:16
  • 3Sungkapalee T, Puntukosit P, Eunsuwan O, et al. lnci dence and clinical manifestations of rotavirus infection among children with acute diarrhea admitted at Buri Ram Hospital, Thailand[J]. Southeast Asian J Trop Med Pub lic Health, 2006,37(6) : 1125-1131.
  • 4Mao M, Yu T, Xiong Y, etal. Effect of a lactose-free milk formula supplemented with bifidobacteria and streptococci on the recovery from acute diarrhea[J]. Asia Pac J Clin Nutr , 2008,17(1) :30-34.
  • 5Swallow DM. Genetics of lactase persistence and lactose in tolerance[J]. Annu Rev Genet ,2003,37:197-219.
  • 6CASPARY W F. Diarrhea associated with carbohydrate malabsorption [ J:. Clin Gastroenterol, 1986,15 (3) :631-651.
  • 7SWALLOW D M. Genetics of lactase persistence and lactose intoler- ance[ J]. Annu Rev Genet ,2003,37 : 197-219.
  • 8安书麟等译,日本株式会社医药杂志社编辑部.最新药物制剂技术及应用[M]中国医药科技出版社,1992.
  • 9吴瑞芳,张建藩.进口医药商品手册[M]中国医药科技出版社,1991.
  • 10金长振.酶学的理论与实际[M]雪谷出版社,1989.

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