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抗甲状腺药物对甲状腺摄^(131)I率影响的比较研究 被引量:5

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摘要 目的 探讨抗甲状腺药物(ATD)对甲状腺摄1 31 I率的影响及其对1 31 I治疗甲亢疗效的影响。方法 经临床症状、体格检查及血清学检查确诊的甲亢患者,分为未服ATD组、服ATD停药>1月组和服ATD停药<1月组。所有患者满足甲状腺摄1 31 I试验要求后作4 h、6 h和2 4 h摄1 31 I率测定,1 31 I治疗采用个性化方案。治疗后3月、6月复查并评价治疗效果。结果 3组患者间甲状腺摄1 31 I率无显著性差异(P>0 .0 5 ) ;但高峰前移发生率在停药<1月组明显高于其它两组(P<0 .0 5 )。总的1 31 I一次治愈率达75 .3% ,但治疗效果在停药<1月组明显低于其他两组(P<0 .0 5 )。结论 ATD对甲状腺摄1 31 I率在停药时间较短时有影响,且主要影响1 31 I的有效半衰期,进一步影响1 31I治疗甲亢的疗效。
作者 潘明志
出处 《四川大学学报(医学版)》 CAS CSCD 北大核心 2005年第3期443-444,共2页 Journal of Sichuan University(Medical Sciences)
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同被引文献53

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