摘要
目的:探讨转移性恶性黑色素瘤的预后因素。方法:回顾性分析93例经病理证实的转移性恶性黑色素瘤患者的临床资料及实验室、影像学检查结果。结果:93例转移性恶性黑色素瘤患者2年生存率为10.8%(10/93)。性别、体质状况、有无肝脏转移、转移部位数目、血清LDH水平、白蛋白水平以及转移灶是否切除对患者的2年生存率有显著影响;而不同年龄患者的2年生存率无统计学差异。结论:女性、体质状况较好、无肝脏转移、单一部位转移、LDH或白蛋白水平正常以及孤立转移病灶的手术切除是预后好的指标。
Objective: To determine clinical prognostic factors that accurately predict survival in patients with metastatic melanoma. Methods: 93 patients with metastatic malignant melanoma were analysed retrospectively. Results: 10.8% of all patients with distant metastasis of melanoma lived for more than 2 years. There was significant difference in 2-year survival rate between men and women,KPS≥80 and <80, liver and without liver involvement,one and multiple organ involvements, normal and elevated serum level of LDH, normal and decreased serum albumin, respectively. There was no difference between≥50 years and <50 years. Conclusion: Female, good performance status, without liver involvement, single organ metastase, normal LDH and albumin level, resection of the isolated focus are highly significant predictors of good survial.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2004年第8期446-448,共3页
Chinese Journal of Clinical Oncology
