摘要
1日龄雏鸡感染鸡传染性贫血病毒（CIAV）后,胸腺和脾脏T淋巴细胞增殖反应分别于14d和7～21d明显减弱（P<O.01,P<0.05）;法氏囊和脾脏B淋巴细胞增殖反应分别于7～21d和21d显著减弱（P<0.01,P<0.05）。由此说明雏鸡感染CIAV后,胸腺、法氏囊和脾脏的细胞免疫功能和/或体液免疫功能均明显降低。此外,雏鸡感染CIAV后14～42d,体重明显降低（P<0.01,P<0.05）,胸腺和法氏囊的重量与体重之比值分别于感染后7～21d和7～14d明显降低（P<0.01,P<0.05）。
Studies were conducted to determine the changes of T and B lymphocyte proliferative responses and the relative weights of the immune organs of chickens infected with chicken infectious anemia virus(CIAV). The proliferative responses of T lymphocytes from both thymus and spleen were all significantly weakened at day 14 and day 7-21 after infection, respectively (P<0. 01,P<0. 05). The proliferative responses of B lymphocytes from Bursa of Fabricius and spleen were noticeably abated at day 7-21 and day 21 after infection, respectively (P<0. 01,P<0. 05). These indicated that the cellular and humoral immune functions were significantly decreased in both the primary and the secondary immune organs of the infected chickens. The thymus-to-body weight ratios and Bursa-to-body weight ratios were markedly reduced at day 7-21 and day 7-14 after infection, respectively (P<0. 01 ,P<0. 05).
出处
《中国兽医学报》
CAS
CSCD
1994年第3期228-231,共4页
Chinese Journal of Veterinary Science
基金
国家自然科学基金资助项目
关键词
鸡病
贫血病毒
感染
免疫系统
雏鸡
Chicken infectious anemia virus
Chicks
lymphocyte proliferative responses
B lymphocyte proliferative responses
