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聚ADP-核糖聚合酶在DNA修复、保持基因组完整性及细胞死亡过程中的作用 被引量:1

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摘要 聚ADP核糖化是细胞在对内外环境的遗传毒物刺激的应答过程中对蛋白质进行翻译后修饰的一种机制,催化此过程的酶即聚ADP 核糖聚合酶。聚ADP核糖化涉及细胞的许多重要功能,如DNA修复、细胞增殖、细胞死亡。
出处 《国外医学(卫生学分册)》 2005年第3期152-155,共4页 Foreign Medical Sciences(Section of Hygiene)
基金 "973"国家重点基础研究发展计划基金资助项目 (2 0 0 2CB5 12 90 4 2 0 0 2CB5 12 90 3)
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同被引文献21

  • 1史海水,廖祥儒,徐祥,梁华平.聚ADP-核糖聚合酶:疾病治疗新靶位[J].生命的化学,2005,25(2):115-118. 被引量:6
  • 2HASSA P O,HOTTIGER M O.An epigenetic code for DNA damage repair pathways[J].Biochem Cell Biol,2005,83(3):270-285.
  • 3MESSNER S,HOTTIGER M O.Histone ADPribosylation in DNA repair,replication and transcription[J].Trends Cell Biol,2011(21):534-542.
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  • 7HUANG Haiyan,CAI Jianfeng,LIU Qincheng,et al.Role of poly(ADP-ribose)glycohydrolase in the regulation of cell fate in response to benzo(a)pyrene[J].Exp Cell Res,2012,318(5):682-690.
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