摘要
本实验比较了不同通气频率时高频双向喷射通气（ＨＦＴＪＶ）与高频喷射通气（ＨＦＪＶ）对组胺致肺损伤犬气体交换、氧运输功能、呼吸力学及血流动力学的影响。结果表明，在组胺持续滴注时，当通气频率分别为６０及１００次／ｍｉｎ时，ＨＦＴＪＶ时的ＰａＣＯ＿２较ＨＦＪＶ时均显著降低（Ｐ＜０．０、１），ｐＨ均显著升高（Ｐ＜０．０１），而ＰａＣＯ＿２、氧耗量、氧运输量、心输出量、肺动脉压、气道压、肺及时吸系统阻力、顺应性等均无明显改变。提示：ＨＦＴＪＶ能够显著增强组胺致肺损伤大的ＣＯ＿２排除，而对氧运输功能、呼吸力学及血流动力学均无明显影响。
Effects of high frequeney two-way iet
ventila-tion ( HFTJV )on gas exchange.oxygen transportfunction、respiratory mechanies and
hemod ynamicparameters were com pared with those of high fre-quency jet ventilation(HFJV) in
dogs withhistamine- induced lung injury. The results showedthat with the ventilatory frequency
of 60 or 100breaths/min PaCO_2was significant lower while pHsignificant highcr in H FTJV than
in HFJV duringhistamine infusion,There were no significant changesin PaO_2, oxygen
consumption.oxygen delivery,Cardiac output,pulmonary arterial pressure,airwaypressure,lung
and respiratory system resistances andcompliances.It is suggested that HFTJV is effectivcin
improving CO_2 elimination in dogs withhistamine-induced lung injury without influcnce inthe
function of oxygen transport,respiratory me-chanics and hemodynamic parameters.
出处
《中国危重病急救医学》
CAS
CSCD
1994年第1期5-7,共3页
Chinese Critical Care Medicine
基金
国家自然科学基金
关键词
气体交换
呼吸
高频喷射通气
组胺
high frequency two-way jet ventilation
Carbon dioxide elimination
oxygen delivery
respiratory
mechanics
