摘要
目的了解外科感染性标本的病原学分布及耐药性,指导临床合理选择抗感染药物。方法回顾性调查557例外科标本的病原菌组成及其耐药性。结果557份外科标本中,总阳性标本344份,阳性率61 .8%;共分离出病原菌422株,分布23个菌种,其中G-菌276株,占65. 4%,G+菌135株,占32. 0%,真菌11株,占2 .6%;大肠埃希菌、金黄色葡萄球菌是外科感染的主要病原菌,各种病原菌的耐药性各不相同。结论外科感染标本的病原菌分布广泛,细菌耐药特性各异,部分标本的多重感染和一些感染菌株的广泛耐药,造成临床经验性使用抗生素失败,临床应根据微生物培养及药物敏感试验结果合理使用抗感染药物,避免抗生素滥用。
OBJECTIVE To study the etiology of surgery infection and the drug resistance characteristic of infective bacteria in order to direct clinic using anti-infective drug reasonably. METHODS The germ composition of 557 surgical specimens and their drug-resistance character were investigated. RESULTS Totally 344 infected specimens were detected, from 422 isolates of 23 species were identified, including 276 Gram-negative bacilli, occupied 65.4%, 135 Gram-positive bacilli, occupied 32.0%, and 11 fungal strains, occupied 2.6%,and their drug-resistance was various, The Escherichia coli and Staphylococcus aureus were the main pathogens in surgical infection. CONCLUSIONS Bacteria that course surgical infection are widespread and their drug resistance character is various. The multiple infection and broad drug resistance are the important matters that making clinical treat failed. Successful treatment would be carried according to the result of germiculture and drug test to avoid drug abusing.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2005年第6期713-715,共3页
Chinese Journal of Nosocomiology
关键词
外科感染
病原菌
耐药性
Surgical infection
Pathogen
Drug-resistance
