摘要
应用红细胞Ｃ３ｂ（ＲＢＣ－Ｃ３ｂ）受体花环试验及红细胞免疫复合物（ＲＢＣ－ＩＣ）花环试验，对６０例风湿性心脏病（简称风心病）患者及７１例正常人的红细胞免疫功能进行了对照研究。结果表明，风心病患者ＲＢＣ－Ｃ３ｂ受体花环率明显低于正常人（Ｐ＜０．０１），ＲＢＣ－ＩＣ花环率明显高于正常人（Ｐ＜０．００１），提示风心病发病与红细胞免疫功能异常有密切关系。风心病患者ＲＢＣ－Ｃ３ｂ受体花环率及ＲＢＣ－ＩＣ花环率与瓣膜损害的数量，无明显关系（Ｐ＞０．０５）。ＲＢＣ－ＩＣ花环率在中至重度心力衰竭组明显高于心功能正常及轻度心力衰竭组（Ｐ＜０．００１），ＲＢＣ－Ｃ３ｂ受体花环率两组无明显差异（Ｐ＞０．０５）。
Sixty patients with rheumatic heart disease (RHD) and 71 normals were studied for red cell immune function by means of the rosette test of red cell C3b receptor and rosette test of red cell immune complex.It was found that the rosette rate of red cell C3b receptor decreased (p<0.01) and rosette rate of red cell immune complex increased (p<0.001)as compared with normals. The results showed that the pathogenesis of RHD may be closely related to the abnormality of red cell immune function. There was no apparent difference among the numbers of affected valves in the patients with RHD (p>0.05).The rosette rate of red cell immune complex in patients with moderate and severe heart failure was higher than in the normals and patients with mild heart failure (p<0.001). However there was no apparent difference in the rosette rate of red cell C3b receptor between them (p>0.05).
出处
《中国循环杂志》
CSCD
1994年第8期459-460,共2页
Chinese Circulation Journal
关键词
风湿性心脏病
红细胞
免疫功能
Rosette of red cell C3b receptor
Rosette of red cell immune complex
Rheumatic heart disease
