摘要
目的探讨应用抗真菌药物预防医院感染的作用。方法采用前瞻性随机对照研究,观察400例患者真菌医院感染情况,对长期使用抗生素、免疫抑制剂和放化疗等相关病例,预防性应用抗真菌药物。结果试验组和对照组发生真菌医院感染发病率分别为6.5%(13/200例)和14%(28/200例),2组间真菌医院感染发病率差异有显著性(P<0.05)。结论对高危患者采取预防性应用抗真菌药物,是降低真菌性医院感染的一种合理、有效的预防措施。
Objective To study the effect of antifungal medicine to prevent nosocomial infection.Methods A prospective randomized control study was used in 400 patients with long time use of antibiotics,immunosuppresant,radiotherapy or chemotherapy.The rate of fungal infection was investigated.Results The rate of fungal infection in study group and control group were 6.5%(13/200) and 14%(28/200),respectively.There was significant difference between the two groups(P<0.05).Conclusion It was easonable and effective to use antifungal medicine to prevent nosocomial fungal infection in high rish patients.
出处
《中国微生态学杂志》
CAS
CSCD
2005年第3期188-189,共2页
Chinese Journal of Microecology
基金
温州市科委课题(S2001A06)
