摘要
３３例急性脑外伤病人伤后２４ｈ内和伤后第５天测定了血浆和脑脊液中Ｄｙｎ—Ａ含量。对照组（ｎ＝１３）血浆和脑脊液中Ｄｙｎ—Ａ含量分别为９３８．７７±３１６．６７ｐｇ／ｍｌ和７７．０８±３２．６５Ｐｇ／ｍｌ；中型脑外伤组为１８７０．３２±５７３．１２ｐｇ／ｍｌ和１８６．３２±５６．３４ｐｇ／ｍｌ，重型脑外伤组为２０３５．１３±６７５．４７ｐｇ／ｍｌ和２２７．５８±１１５．７７ｐｇ／ｍｌ，均明显高于对照组（Ｐ＜０．０１）。随着病情的好转Ｄｙｎ—Ａ含量亦随之降低，提示Ｄｙｎ—Ａ参与脑外伤的发病过程，其血浆和脑脊液中Ｄｙｎ—Ａ含量的变化对判断脑外伤病情的轻重和估价预后，有重要意义。
Dynorphin A in the plasma and CSF were measured in 33 patients with acute head injuries and 13 controls.The mean values of dynorphin A in plasma and CSF were 938.77±316.67 pg/ml and 77.08±32. 65 pg/ml in the controls;1870.32±573. 12 pg/ml amd 186.32±56.34 pg/mlh patients wtih moderate head injury; 2035.13±675.47 pg/ml and 227.58±115.77 Pg/ml in Patients with severe head injury respectively(P<0.01).The levels of dynorphln A in plasma and CSF decreased as patients got better.We consider it valuable to indicate the disease seventy and to Predict the Prognosis of cerebral injury.
出处
《中国冶金工业医学杂志》
1994年第2期71-73,共3页
Chinese Medical Journal of Metallurgical industry
